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Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

McLaughlin JN, Shen L, Holinstat M, Brooks JD, Dibenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. J Biol Chem. 2005 Jul 1; 280(26):25048-59.

View in: PubMed

subject areas
  • Actins
  • Adenosine Diphosphate
  • Amides
  • Calcium
  • Cells, Cultured
  • Chelating Agents
  • Dipeptides
  • Dose-Response Relationship, Drug
  • Egtazic Acid
  • Electric Impedance
  • Endothelium, Vascular
  • Enzyme Inhibitors
  • GTP-Binding Protein alpha Subunits, G12-G13
  • GTP-Binding Protein alpha Subunits, Gq-G11
  • GTP-Binding Proteins
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Kinetics
  • Ligands
  • Matrix Metalloproteinase Inhibitors
  • Microcirculation
  • Models, Biological
  • Models, Theoretical
  • Peptides
  • Pertussis Toxin
  • Protease Inhibitors
  • Protein Binding
  • Protein-Serine-Threonine Kinases
  • Pyridines
  • Receptor, PAR-1
  • rho-Associated Kinases
  • Signal Transduction
  • Thrombin
  • Time Factors

authors with profiles
  • Michael Holinstat



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