Thomas Jefferson University

Timothy Mosca

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentDepartment of Neurosciences
Address900 Walnut Street
Philadelphia PA 19107
Phone215-955-2670
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dresselhaus EC, Harris KP, Blanchette CR, Koles K, Del Signore SJ, Pescosolido MF, Ermanoska B, Rozencwaig M, Soslowsky RC, Parisi MJ, Stewart BA, Mosca TJ, Rodal AA. ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles. J Cell Biol. 2024 Sep 02; 223(9). PMID: 38842573.
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    2. DePew AT, Bruckner JJ, O'Connor-Giles KM, Mosca TJ. Neuronal LRP4 directs the development, maturation and cytoskeletal organization of Drosophila peripheral synapses. Development. 2024 Jun 01; 151(11). PMID: 38738619.
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    3. Dresselhaus EC, Harris KP, Blanchette CR, Koles K, Del Signore SJ, Pescosolido MF, Ermanoska B, Rozencwaig M, Soslowsky RC, Parisi MJ, Stewart BA, Mosca TJ, Rodal AA. ESCRT disruption provides evidence against transsynaptic signaling functions for extracellular vesicles. bioRxiv. 2024 May 05. PMID: 38746182.
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    4. DePew AT, Bruckner JJ, O'Connor-Giles KM, Mosca TJ. Neuronal LRP4 directs the development, maturation, and cytoskeletal organization of peripheral synapses. bioRxiv. 2023 Nov 08. PMID: 37961323.
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    5. Aimino MA, Humenik J, Parisi MJ, Duhart JC, Mosca TJ. SynLight: a bicistronic strategy for simultaneous active zone and cell labeling in the Drosophila nervous system. G3 (Bethesda). 2023 Sep 27. PMID: 37757863.
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    6. Aimino MA, Humenik J, Parisi MJ, Duhart JC, Mosca TJ. SynLight: a dicistronic strategy for simultaneous active zone and cell labeling in the Drosophila nervous system. bioRxiv. 2023 Jul 17. PMID: 37502901.
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    7. Parisi MJ, Aimino MA, Mosca TJ. A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila. Cell Rep Methods. 2023 May 22; 3(5):100477. PMID: 37323572.
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    8. Aimino MA, DePew AT, Restrepo L, Mosca TJ. Synaptic Development in Diverse Olfactory Neuron Classes Uses Distinct Temporal and Activity-Related Programs. J Neurosci. 2023 Jan 04; 43(1):28-55. PMID: 36446587.
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    9. Duhart JC, Mosca TJ. Genetic regulation of central synapse formation and organization in Drosophila melanogaster. Genetics. 2022 Jun 02. PMID: 35652253.
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    10. Restrepo LJ, DePew AT, Moese ER, Tymanskyj SR, Parisi MJ, Aimino MA, Duhart JC, Fei H, Mosca TJ. ?-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor. Dev Cell. 2022 May 25. PMID: 35654038.
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    11. DePew AT, Mosca TJ. Conservation and Innovation: Versatile Roles for LRP4 in Nervous System Development. J Dev Biol. 2021 Mar 14; 9(1). PMID: 33799485.
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    12. Sapiro AL, Freund EC, Restrepo L, Qiao HH, Bhate A, Li Q, Ni JQ, Mosca TJ, Li JB. Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons. Cell Rep. 2020 May 19; 31(7):107654. PMID: 32433963.
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    13. DePew AT, Aimino MA, Mosca TJ. The Tenets of Teneurin: Conserved Mechanisms Regulate Diverse Developmental Processes in the Drosophila Nervous System. Front Neurosci. 2019; 13:27. PMID: 30760977.
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    14. Beier KT, Kim CK, Hoerbelt P, Hung LW, Heifets BD, DeLoach KE, Mosca TJ, Neuner S, Deisseroth K, Luo L, Malenka RC. Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature. 2017 09 21; 549(7672):345-350. PMID: 28902833.
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    15. Mosca TJ. Drosophila mutants lacking octopamine exhibit impairment in aversive olfactory associative learning (Commentary on Iliadi et al. (2017)). Eur J Neurosci. 2017 Sep; 46(5):2078-2079. PMID: 28715089.
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    16. Mosca TJ, Luginbuhl DJ, Wang IE, Luo L. Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons. Elife. 2017 Jun 13; 6. PMID: 28606304.
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    17. Sakuma C, Saito Y, Umehara T, Kamimura K, Maeda N, Mosca TJ, Miura M, Chihara T. The Strip-Hippo Pathway Regulates Synaptic Terminal Formation by Modulating Actin Organization at the Drosophila Neuromuscular Synapses. Cell Rep. 2016 Aug 30; 16(9):2289-97. PMID: 27545887; PMCID: PMC5023852.
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    18. Mosca TJ. On the Teneurin track: a new synaptic organization molecule emerges. Front Cell Neurosci. 2015; 9:204. PMID: 26074772; PMCID: PMC4444827.
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    19. Mosca TJ, Luo L. Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins. Elife. 2014 Oct 13; 3:e03726. PMID: 25310239; PMCID: PMC4194450.
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    20. Yu XM, Gutman I, Mosca TJ, Iram T, Ozkan E, Garcia KC, Luo L, Schuldiner O. Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-ß signaling. Neuron. 2013 May 08; 78(3):456-68. PMID: 23664613; PMCID: PMC3706783.
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    21. Mosca TJ, Hong W, Dani VS, Favaloro V, Luo L. Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice. Nature. 2012 Mar 18; 484(7393):237-41. PMID: 22426000; PMCID: PMC3326183.
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    22. Hong W, Mosca TJ, Luo L. Teneurins instruct synaptic partner matching in an olfactory map. Nature. 2012 Mar 18; 484(7393):201-7. PMID: 22425994; PMCID: PMC3345284.
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    23. Mosca TJ, Schwarz TL. Drosophila Importin-a2 is involved in synapse, axon and muscle development. PLoS One. 2010 Dec 06; 5(12):e15223. PMID: 21151903; PMCID: PMC2997784.
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    24. Mosca TJ, Schwarz TL. The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nat Neurosci. 2010 Aug; 13(8):935-43. PMID: 20601947; PMCID: PMC2913881.
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    25. Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL. Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci. 2010 Apr 14; 30(15):5253-68. PMID: 20392948; PMCID: PMC2881940.
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    26. Mosca TJ, Carrillo RA, White BH, Keshishian H. Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3477-82. PMID: 15728380; PMCID: PMC552910.
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