"Substance P" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
| Descriptor ID |
D013373
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| MeSH Number(s) |
D12.644.276.812.900.866 D12.644.400.800.750 D12.644.456.800.866 D12.776.467.812.900.866 D12.776.631.650.800.750 D23.469.050.375.850.890 D23.529.812.900.866
|
| Concept/Terms |
Substance P- Substance P
- Euler-Gaddum Substance P
- Euler Gaddum Substance P
- Substance P, Euler-Gaddum
- SP(1-11)
|
Below are MeSH descriptors whose meaning is more general than "Substance P".
Below are MeSH descriptors whose meaning is more specific than "Substance P".
This graph shows the total number of publications written about "Substance P" by people in this website by year, and whether "Substance P" was a major or minor topic of these publications.
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Below are the most recent publications written about "Substance P" by people in Profiles.
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Lantz C, Xi Z, Rider RL, Walker TE, Hebert M, Russell DH. Temperature-Dependent Trimethylamine N-Oxide Induced the Formation of Substance P Dimers. J Phys Chem B. 2024 11 21; 128(46):11369-11378.
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Veruva SY, Lanman TH, Isaza JE, Freeman TA, Kurtz SM, Steinbeck MJ. Periprosthetic UHMWPE Wear Debris Induces Inflammation, Vascularization, and Innervation After Total Disc Replacement in the Lumbar Spine. Clin Orthop Relat Res. 2017 May; 475(5):1369-1381.
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Kepler CK, Markova DZ, Koerner JD, Mendelis J, Chen CM, Vaccaro AR, Risbud MV, Albert TJ, Anderson DG. Substance P Receptor Antagonist Suppresses Inflammatory Cytokine Expression in Human Disc Cells. Spine (Phila Pa 1976). 2015 Aug 15; 40(16):1261-9.
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Kepler CK, Markova DZ, Hilibrand AS, Vaccaro AR, Risbud MV, Albert TJ, Anderson DG. Substance P stimulates production of inflammatory cytokines in human disc cells. Spine (Phila Pa 1976). 2013 Oct 01; 38(21):E1291-9.
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Elliott MB, Oshinsky ML, Amenta PS, Awe OO, Jallo JI. Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. Headache. 2012 Jun; 52(6):966-84.
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Vera PL, Iczkowski KA, Leng L, Bucala R, Meyer-Siegler KL. Macrophage migration inhibitory factor is released as a complex with alpha1-inhibitor-3 in the intraluminal fluid during bladder inflammation in the rat. J Urol. 2005 Jul; 174(1):338-43.
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Sun Z, Del Mar N, Meade C, Goldowitz D, Reiner A. Differential changes in striatal projection neurons in R6/2 transgenic mice for Huntington's disease. Neurobiol Dis. 2002 Dec; 11(3):369-85.
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Anand P, Terenghi G, Warner G, Kopelman P, Williams-Chestnut RE, Sinicropi DV. The role of endogenous nerve growth factor in human diabetic neuropathy. Nat Med. 1996 Jun; 2(6):703-7.
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Kwatra MM, Schwinn DA, Schreurs J, Blank JL, Kim CM, Benovic JL, Krause JE, Caron MG, Lefkowitz RJ. The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2. J Biol Chem. 1993 May 05; 268(13):9161-4.
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Yeo CJ, Couse NF, Zinner MJ. Serotonin and substance P stimulate intestinal secretion in the isolated perfused ileum. Surgery. 1989 Jan; 105(1):86-92.