Felix Kim

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-9270
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Melillo RJ, El Khoury C, Shaver AL, Cunningham M, Benavides N, Lacerda Q, Kim FJ, Leader AE. A student-community partnership to enhance cancer research training. BMC Med Educ. 2024 Oct 17; 24(1):1164. PMID: 39420298.
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    2. Zhang Z, Luo R, Kelly WK, Chen J, Donahue S, Ip K, Handley NR, Tester WJ, Tsang ML, Kim FJ, Myers R, Lu-Yao G, Gu J, Lin J, Li B, Wang C, Yang H. Prostein expression on circulating tumor cells as a prognostic marker in metastatic castration-resistant prostate cancer. Prostate Cancer Prostatic Dis. 2023 Dec 06. PMID: 38057610.
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    3. Oyer HM, Steck AR, Longen CG, Venkat S, Bayrak K, Munger EB, Fu D, Castagnino PA, Sanders CM, Tancler NA, Mai MT, Myers JP, Schiewer MJ, Chen N, Mostaghel EA, Kim FJ. Sigma1 Regulates Lipid Droplet-mediated Redox Homeostasis Required for Prostate Cancer Proliferation. Cancer Res Commun. 2023 10 30; 3(10):2195-2210. PMID: 37874216.
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    4. Fradin J, Kim FJ, Lu-Yao GL, Storozynsky E, Kelly WK. Review of Cardiovascular Risk of Androgen Deprivation Therapy and the Influence of Race in Men with Prostate Cancer. Cancers (Basel). 2023 Apr 15; 15(8). PMID: 37190244.
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    5. Friedman GD, Habel LA, Achacoso N, Sanders CM, Oyer HM, Fireman B, Van Den Eeden SK, Kim FJ. Haloperidol and Prostate Cancer Prevention: More Epidemiologic Research Needed. Perm J. 2020; 24. PMID: 31852040.
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    6. Oyer HM, Sanders CM, Kim FJ. Small-Molecule Modulators of Sigma1 and Sigma2/TMEM97 in the Context of Cancer: Foundational Concepts and Emerging Themes. Front Pharmacol. 2019; 10:1141. PMID: 31695608.
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    7. Kim FJ, Pasternak GW. s1 Receptor ligand binding: an open-and-shut case. Nat Struct Mol Biol. 2018 Oct 11. PMID: 30310147.
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    8. Maher CM, Thomas JD, Haas DA, Longen CG, Oyer HM, Tong JY, Kim FJ. Small-Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1. Mol Cancer Res. 2018 02; 16(2):243-255. PMID: 29117944.
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    9. Kim FJ, Pasternak GW. Cloning the sigma2 receptor: Wandering 40 years to find an identity. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):6888-6890. PMID: 28645899.
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    10. Salvino JM, Srikanth YVV, Lou R, Oyer HM, Chen N, Kim FJ. Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer. Bioorg Med Chem Lett. 2017 05 15; 27(10):2216-2220. PMID: 28385503.
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    11. Thomas JD, Longen CG, Oyer HM, Chen N, Maher CM, Salvino JM, Kania B, Anderson KN, Ostrander WF, Knudsen KE, Kim FJ. Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. Cancer Res. 2017 May 01; 77(9):2439-2452. PMID: 28235766.
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    12. Barrett JE, Kim FJ. The purpose of repurposing. Oncotarget. 2017 02 21; 8(8):12534-12535. PMID: 28129642.
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    13. Kim FJ. Introduction to Sigma Proteins: Evolution of the Concept of Sigma Receptors. Handb Exp Pharmacol. 2017; 244:1-11. PMID: 28871306.
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    14. Kim FJ, Maher CM. Sigma1 Pharmacology in the Context of Cancer. Handb Exp Pharmacol. 2017; 244:237-308. PMID: 28744586.
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    15. Vorobyeva AG, Lee R, Miller S, Longen C, Sharoni M, Kandelwal PJ, Kim FJ, Marenda DR, Saunders AJ. Cyclopamine modulates ?-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradation. J Biol Chem. 2014 Nov 28; 289(48):33258-74. PMID: 25281744.
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    16. Schrock JM, Spino CM, Longen CG, Stabler SM, Marino JC, Pasternak GW, Kim FJ. Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress. Mol Pharmacol. 2013 Nov; 84(5):751-62. PMID: 24006496; PMCID: PMC3807076.
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    17. Kim FJ, Schrock JM, Spino CM, Marino JC, Pasternak GW. Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun. 2012 Sep 21; 426(2):177-82. PMID: 22925888; PMCID: PMC3480203.
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    18. Kim FJ, Kovalyshyn I, Burgman M, Neilan C, Chien CC, Pasternak GW. Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding. Mol Pharmacol. 2010 Apr; 77(4):695-703. PMID: 20089882; PMCID: PMC2845939.
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