"Tenuazonic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
Descriptor ID |
D013720
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MeSH Number(s) |
D03.383.773.812.900 D23.946.587.915
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tenuazonic Acid".
Below are MeSH descriptors whose meaning is more specific than "Tenuazonic Acid".
This graph shows the total number of publications written about "Tenuazonic Acid" by people in this website by year, and whether "Tenuazonic Acid" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tenuazonic Acid" by people in Profiles.
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Cherian PT, Wu X, Yang L, Scarborough JS, Singh AP, Alam ZA, Lee RE, Hurdle JG. Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection. J Antimicrob Chemother. 2015 Nov; 70(11):3061-9.
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Cherian PT, Wu X, Maddox MM, Singh AP, Lee RE, Hurdle JG. Chemical modulation of the biological activity of reutericyclin: a membrane-active antibiotic from Lactobacillus reuteri. Sci Rep. 2014 Apr 17; 4:4721.