"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
|
| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
|
| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
|
Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Tazzeo T, Bates G, Roman HN, Lauzon AM, Khasnis MD, Eto M, Janssen LJ. Caffeine relaxes smooth muscle through actin depolymerization. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15; 303(4):L334-42.
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O'Malley MA, Naranjo AN, Lazarova T, Robinson AS. Analysis of adenosine A2a receptor stability: effects of ligands and disulfide bonds. Biochemistry. 2010 Nov 2; 49(43):9181-9.
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Nunnari G, Argyris E, Fang J, Mehlman KE, Pomerantz RJ, Daniel R. Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines. Virology. 2005 May 10; 335(2):177-84.