"Thromboxane-A Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
| Descriptor ID |
D013930
|
| MeSH Number(s) |
D08.811.399.475.900
|
| Concept/Terms |
Thromboxane-A Synthase- Thromboxane-A Synthase
- Synthase, Thromboxane-A
- Thromboxane A2 Synthetase
- A2 Synthetase, Thromboxane
- Synthetase, Thromboxane A2
- Thromboxane Synthetase
- Synthetase, Thromboxane
- Thromboxane A Synthase
- Synthase, Thromboxane A
|
Below are MeSH descriptors whose meaning is more general than "Thromboxane-A Synthase".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane-A Synthase".
This graph shows the total number of publications written about "Thromboxane-A Synthase" by people in this website by year, and whether "Thromboxane-A Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
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Below are the most recent publications written about "Thromboxane-A Synthase" by people in Profiles.
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Golino P, Ragni M, Cirillo P, Pascucci I, Ezekowitz MD, Pawashe A, Scognamiglio A, Pace L, Guarino A, Chiariello M. Aurintricarboxylic acid reduces platelet deposition in stenosed and endothelially injured rabbit carotid arteries more effectively than other antiplatelet interventions. Thromb Haemost. 1995 Sep; 74(3):974-9.
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Patrono C, Patrignani P, Rocca B, Landolfi R. Characterization of biochemical and functional effects of antiplatelet drugs as a key to their clinical development. Thromb Haemost. 1995 Jul; 74(1):396-400.
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Suzuki S, Sano K, Handa H, Asano T, Tamura A, Yonekawa Y, Ono H, Tachibana N, Hanaoka K. Clinical study of OKY-046, a thromboxane synthetase inhibitor, in prevention of cerebral vasospasms and delayed cerebral ischaemic symptoms after subarachnoid haemorrhage due to aneurysmal rupture: a randomized double-blind study. Neurol Res. 1989 Jun; 11(2):79-88.
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O'Connor KM, Friehling TD, Kowey PR. The effect of thromboxane inhibition on vulnerability to ventricular fibrillation in the acute and chronic feline infarction models. Am Heart J. 1989 Apr; 117(4):848-53.
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O'Connor KM, Friehling TD, Kelliher GJ, MacNab MW, Wetstein L, Kowey PR. Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion. Am Heart J. 1986 Apr; 111(4):683-8.
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Reibel DK, Roth DM, Lefer BL, Lefer AM. Hyperreactivity of coronary vasculature in platelet-perfused hearts from diabetic rats. Am J Physiol. 1983 Oct; 245(4):H640-5.
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Ingerman-Wojenski C, Silver MJ, Smith JB, Macarak E. Bovine endothelial cells in culture produce thromboxane as well as prostacyclin. J Clin Invest. 1981 May; 67(5):1292-6.