Timolol

"Timolol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.

Descriptor ID	D013999
MeSH Number(s)	D02.033.100.624.915 D02.033.755.624.915 D02.092.063.624.915 D02.886.675.867.768 D03.383.129.708.867.768 D03.383.533.640.775
Concept/Terms	Timolol Timolol (S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol Timolol Hemihydrate Hemihydrate, Timolol L-714,465 L-714,465 L 714,465 L714,465 MK-950 MK-950 MK 950 MK950 Optimol Optimol Timolol Maleate Timolol Maleate Timolol Maleate, (1:1) Salt Timoptic Timoptic Timoptol Timoptol Blocadren Blocadren Timacar Timacar

Below are MeSH descriptors whose meaning is more general than "Timolol".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Propanolamines [D02.033.100.624]
Timolol [D02.033.100.624.915]
Propanols [D02.033.755]
Propanolamines [D02.033.755.624]
Timolol [D02.033.755.624.915]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Propanolamines [D02.092.063.624]
Timolol [D02.092.063.624.915]
Sulfur Compounds [D02.886]
Thiazoles [D02.886.675]
Thiadiazoles [D02.886.675.867]
Timolol [D02.886.675.867.768]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Thiazoles [D03.383.129.708]
Thiadiazoles [D03.383.129.708.867]
Timolol [D03.383.129.708.867.768]
Oxazines [D03.383.533]
Morpholines [D03.383.533.640]
Timolol [D03.383.533.640.775]

Below are MeSH descriptors whose meaning is related to "Timolol".

Below are MeSH descriptors whose meaning is more specific than "Timolol".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Timolol" by people in this website by year, and whether "Timolol" was a major or minor topic of these publications.

Bar chart showing 13 publications over 9 distinct years, with a maximum of 3 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	1	2
2005	2	1	3
2008	0	1	1
2009	1	0	1
2012	1	0	1
2014	0	1	1
2016	1	0	1
2020	1	1	2
2021	1	0	1

Below are the most recent publications written about "Timolol" by people in Profiles.

Obeid A, Hsu J, Ehmann D, Gao X, Sridhar J, Chiang A, Park CH, Ho AC. TOPICAL DORZOLAMIDE-TIMOLOL WITH INTRAVITREOUS ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL VEIN OCCLUSION: A PILOT STUDY. Retin Cases Brief Rep. 2021 Mar 01; 15(2):120-126.

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Singh IP, Fechtner RD, Myers JS, Kim T, Usner DW, McKee H, Sheng H, Lewis RA, Heah T, Kopczynski CC. Pooled Efficacy and Safety Profile of Netarsudil Ophthalmic Solution 0.02% in Patients With Open-angle Glaucoma or Ocular Hypertension. J Glaucoma. 2020 10; 29(10):878-884.

View in: PubMed
Hsu J, Patel SN, Wolfe JD, Shah CP, Chen E, Jenkins TL, Wibbelsman TD, Obeid A, Mikhail M, Garg SJ, Ho AC, Chiang A, Spirn MJ, Vander JF. Effect of Adjuvant Topical Dorzolamide-Timolol vs Placebo in Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial. JAMA Ophthalmol. 2020 05 01; 138(5):560-567.

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Sridhar J, Hsu J, Shahlaee A, Garg SJ, Spirn MJ, Fineman MS, Vander J. Topical Dorzolamide-Timolol With Intravitreous Anti-Vascular Endothelial Growth Factor for Neovascular Age-Related Macular Degeneration. JAMA Ophthalmol. 2016 Apr; 134(4):437-43.

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Hsu J, Gerstenblith AT, London NJ, Garg SJ, Spirn MJ, Maguire JI, Park C, Sivalingam A. Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment. Retina. 2014 Dec; 34(12):2458-61.

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Shah CP, Hsu J, Spirn MJ, Donoso L, Garg SJ. Topical aqueous suppression does not significantly affect duration of intraocular gas tamponade after vitrectomy. Retina. 2012 Jan; 32(1):168-71.

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Jay Katz L, Myers JS. Smoothing the intraocular pressure roller coaster: a new goal? Am J Ophthalmol. 2009 Aug; 148(2):177-8.

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Fudemberg SJ, Batiste C, Katz LJ. Efficacy, safety, and current applications of brimonidine. Expert Opin Drug Saf. 2008 Nov; 7(6):795-9.

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Schuman JS, Katz GJ, Lewis RA, Henry JC, Mallick S, Wells DT, Sullivan EK, Landry TA, Bergamini MV, Robertson SM. Efficacy and safety of a fixed combination of travoprost 0.004%/timolol 0.5% ophthalmic solution once daily for open-angle glaucoma or ocular hypertension. Am J Ophthalmol. 2005 Aug; 140(2):242-50.

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Henderer JD, Wilson RP, Moster MR, Myers J, Schmidt C, Fontanarosa J, Steinmann WC. Timolol/dorzolamide combination therapy as initial treatment for intraocular pressure over 30 mm Hg. J Glaucoma. 2005 Aug; 14(4):267-70.

View in: PubMed

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