Tosylphenylalanyl Chloromethyl Ketone
"Tosylphenylalanyl Chloromethyl Ketone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
| Descriptor ID |
D014108
|
| MeSH Number(s) |
D02.455.426.559.389.832.710 D02.886.590.887.660 D12.125.065.930
|
| Concept/Terms |
Tosylphenylalanyl Chloromethyl Ketone- Tosylphenylalanyl Chloromethyl Ketone
- Chloromethyl Ketone, Tosylphenylalanyl
- Ketone, Tosylphenylalanyl Chloromethyl
- Tosylphenylalanyl Chloromethane
- Chloromethane, Tosylphenylalanyl
- TPCK
- Chlorophenyltosylamidobutanone
|
Below are MeSH descriptors whose meaning is more general than "Tosylphenylalanyl Chloromethyl Ketone".
Below are MeSH descriptors whose meaning is more specific than "Tosylphenylalanyl Chloromethyl Ketone".
This graph shows the total number of publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in this website by year, and whether "Tosylphenylalanyl Chloromethyl Ketone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in Profiles.
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Alugupalli KR, Kalfas S. Degradation of lactoferrin by periodontitis-associated bacteria. FEMS Microbiol Lett. 1996 Dec 01; 145(2):209-14.
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Slaga TJ, Fischer SM, Weeks CE, Nelson K, Mamrack M, Klein-Szanto AJ. Specificity and mechanism(s) of promoter inhibitors in multistage promotion. Carcinog Compr Surv. 1982; 7:19-34.
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Slaga TJ, Klein-Szanto AJ, Fischer SM, Weeks CE, Nelson K, Major S. Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):2251-4.
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Malemud CJ, Janoff A. Identification of neutral proteases in human neutrophil granules that degrade articular cartilage proteoglycan. Arthritis Rheum. 1975 Jul-Aug; 18(4):361-8.