"Trimethoprim" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
| Descriptor ID |
D014295
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| MeSH Number(s) |
D03.383.742.906
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trimethoprim".
Below are MeSH descriptors whose meaning is more specific than "Trimethoprim".
This graph shows the total number of publications written about "Trimethoprim" by people in this website by year, and whether "Trimethoprim" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trimethoprim" by people in Profiles.
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Botros C, Lozo S, Iyer S, Warren A, Goldberg R, Tomezsko J, Sasso K, Sand P, Gafni-Kane A, Biener A, Botros-Brey S. Methenamine hippurate compared with trimethoprim for the prevention of recurrent urinary tract infections: a randomized clinical trial. Int Urogynecol J. 2022 Mar; 33(3):571-580.
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Rajagopal K. Commentary: Preprocedural diagnostic imaging for transcatheter aortic valve implantation-Videri quam esse. J Thorac Cardiovasc Surg. 2021 10; 162(4):1085-1086.
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Milder E, Vander J, Shah C, Garg S. Changes in antibiotic resistance patterns of conjunctival flora due to repeated use of topical antibiotics after intravitreal injection. Ophthalmology. 2012 Jul; 119(7):1420-4.
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Popov VM, Chan DC, Fillingham YA, Atom Yee W, Wright DL, Anderson AC. Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative. Bioorg Med Chem Lett. 2006 Aug 15; 16(16):4366-70.