Thomas Jefferson University

Rupsa Boelig

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentObstetrics-Gynecology
Address833 Chestnut Street
Philadelphia PA 19107
Phone215-955-9196
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Adegboyega O, Gayen Nee' Betal S, Urday P, Huang R, Bodycot K, Al-Kouatly HB, Solarin K, Chan JSY, Addya S, Boelig RC, Aghai ZH. DNA methylation patterns in umbilical cord blood from infants of methadone maintained opioid dependent mothers. Sci Rep. 2024 Jul 27; 14(1):17298. PMID: 39068260.
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    2. Boelig RC, Lam K, Rochani A, Soni V, Kaushal G, Kraft WK. Azithromycin Dosing and Preterm premature rupture of membranes Treatment (ADAPT): A randomized controlled Phase I trial. Am J Obstet Gynecol MFM. 2024 Jul 06; 101423. PMID: 38977063.
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    3. Iyer NS, Ferguson EB, Yan VZ, Hand DJ, Abatemarco DJ, Boelig RC. Standard Versus Rapid Inpatient Methadone Titration for Pregnant Patients With Opioid Use Disorder: A Retrospective Cohort Study. J Addict Med. 2024 Jun 24. PMID: 38912695.
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    4. Tolosa JE, Boelig RC, Bell J, Mart?nez-Baladejo M, Stoltzfus J, Mateus J, Qui?ones JN, Galeano-Herrera S, Pereira L, Burwick R, L?pez-Torres L, Valencia C, Berghella V. Concurrent Progestogen and Cerclage to Reduce Preterm Birth: a multicenter international retrospective cohort. Am J Obstet Gynecol MFM. 2024 Mar 19; 101351. PMID: 38513806.
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    5. Boudova S, Tholey D, Fenkel JM, Derman R, Boelig RC. Pregnancy as an Opportunity for Hepatitis C Virus Elimination and Eradication. Am J Trop Med Hyg. 2023 Dec 26. PMID: 38150734.
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    6. Boelig RC, Kaushal G, Rochani A, McKenzie S, Kraft WK. Aspirin pharmacokinetics and pharmacodymamics through gestation. Am J Obstet Gynecol. 2023 Dec 23. PMID: 38145726.
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    7. Derman RJ, Bellad RB, Bellad MB, Bradford-Rogers J, Georgieff MK, Aghai ZH, Thind S, Auerbach M, Boelig R, Leiby BE, Short V, Yogeshkumar S, Charantimath US, Somannavar MS, Mallapur AA, Pol R, Ramadurg U, Sangavi R, Peerapur BV, Banu N, Patil PS, Patil AP, Roy S, Vastrad P, Wallace D, Shah H, Goudar SS. RAPIDIRON Trial follow-up study - the RAPIDIRON-KIDS Study: protocol of a prospective observational follow-up study. Trials. 2023 Dec 20; 24(1):818. PMID: 38124098.
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    8. Rana T, Gulersen M, Roman A, Boelig RC, Berghella V. Reply to: Vaginal progesterone should be offered to patients with a singleton gestation and a history of spontaneous preterm birth only if a cervical length =25 mm is detected at midtrimester. Am J Obstet Gynecol MFM. 2023 Nov 04; 101216. PMID: 37931780.
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    9. Boelig RC, Chaudhury S, Gromowski GD, Mayer S, King J, Aghai ZH, Bergmann-Leitner E. Reduced maternal immunity and vertical transfer of immunity against SARS-CoV-2 variants of concern with COVID-19 exposure or initial vaccination in pregnancy. Front Immunol. 2023; 14:1216410. PMID: 37753075.
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    10. Berghella V, Gulersen M, Roman A, Boelig RC. Vaginal progesterone for the prevention of recurrent spontaneous preterm birth. Am J Obstet Gynecol MFM. 2023 Aug 03; 5(10):101116. PMID: 37543143.
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    11. Urday P, Gayen Nee' Betal S, Sequeira Gomes R, Al-Kouatly HB, Solarin K, Chan JS, Li D, Rahman I, Addya S, Boelig RC, Aghai ZH. SARS-CoV-2 Covid-19 Infection During Pregnancy and Differential DNA Methylation in Human Cord Blood Cells From Term Neonates. Epigenet Insights. 2023; 16:25168657231184665. PMID: 37425024.
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    12. Abelman SH, Svetec S, Felder L, Boelig RC. Impact of telehealth implementation on diagnosis of hypertensive disorders of pregnancy. Am J Obstet Gynecol MFM. 2023 Jun 02; 5(8):101043. PMID: 37271196.
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    13. Boelig RC. Obstetric Indications for Progestin Therapy. Obstet Gynecol Clin North Am. 2023 Mar; 50(1):101-107. PMID: 36822696.
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    14. Roman A, Gulersen M, Boelig RC, Berghella V. Proposed staging criteria for sonographic and physical exam for cervical changes at <24 weeks gestation to predict preterm birth. Am J Obstet Gynecol MFM. 2023 Jan; 5(1):100753. PMID: 36130675.
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    15. Boelig RC, Cahanap TJ, Ma L, Zhan T, Berghella V, Chan JSY, Kraft WK, Mckenzie SE. Platelet protease activated receptor 4 (PAR 4) Receptor Genotype is Associated with an Increased Risk of Preterm Birth. J Thromb Haemost. 2022 Jul 11. PMID: 35815338.
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    16. Boelig RC, Saccone G, Berghella V. Reply Quality assessment of studies included in systematic reviews. Am J Obstet Gynecol MFM. 2022 May 31; 100665. PMID: 35662593.
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    17. Boelig RC, Aghai Z, Chauhdury S, Kazan A, Chan JS, Bergmann-Leitner E. Impact of COVID-19 disease and vaccination on maternal/fetal inflammatory response, placental pathology, and perinatal outcomes. Am J Obstet Gynecol. 2022 May 28. PMID: 35640704.
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    18. Boelig RC, Mcintosh J, Feltovich H, House M. Cervical Length Ultrasound for the Evaluation of Preterm Labor: A Survey of National Use and Review of Evidence. Am J Perinatol. 2022 May 17. PMID: 35580624.
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    19. Boelig RC, Locci M, Saccone G, Gragnano E, Berghella V. Vaginal progesterone compared with intramuscular 17-alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth in singleton gestations: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2022 May 10; 4(5):100658. PMID: 35562009.
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    20. Gayen Nee' Betal S, Urday P, Al-Kouatly HB, Solarin K, Chan JSY, Addya S, Boelig RC, Aghai ZH. COVID-19 Infection During Pregnancy Induces Differential Gene Expression in Human Cord Blood Cells From Term Neonates. Front Pediatr. 2022; 10:834771. PMID: 35547542.
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    21. Boelig RC, Schoen CN, Frey H, Gimovsky AC, Springel E, Backley S, Berghella V. Vaginal progesterone versus Intramuscular 17-hydroxyprogesterone caproate for Prevention of recurrent preterm birth (VIP): a randomized controlled trial. Am J Obstet Gynecol. 2022 Feb 18. PMID: 35189093.
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    22. Boelig RC, Chaudhury S, Aghai ZH, Oliver EA, Mancuso F, Berghella V, Bergmann-Leitner ES. Comprehensive serologic profile and specificity of maternal and neonatal cord blood SARS-CoV-2 antibodies. AJOG Glob Rep. 2022 Feb; 2(1):100046. PMID: 34961853.
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    23. Boelig RC, Chaudhury S, Aghai ZH, Oliver E, Manusco F, Berghella V, Bergmann-Leitner E. Comprehensive Serological Profile and Specificity of Maternal and Neonatal Cord Blood SARS CoV-2 Antibodies. medRxiv. 2021 Dec 07. PMID: 34909795.
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    24. Wang X, Garcia SM, Kellom KS, Boelig RC, Matone M. Eligibility, Utilization, and Effectiveness of 17-Alpha Hydroxyprogesterone Caproate (17OHPC) in a Statewide Population-Based Cohort of Medicaid Enrollees. Am J Perinatol. 2021 Nov 16. PMID: 34784617.
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    25. Boelig RC, Roman A, Berghella V. Screening for preterm birth prevention: more than just one number? Am J Obstet Gynecol. 2021 Oct 16. PMID: 34666053.
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    26. Derman RJ, Goudar SS, Thind S, Bhandari S, Aghai Z, Auerbach M, Boelig R, Charantimath US, Frasso R, Ganachari MS, Gaur KL, Georgieff MK, Jaeger F, Yogeshkumar S, Lalakia P, Leiby B, Majumdar M, Mehta A, Mehta S, Mehta S, Mennemeyer ST, Revankar AP, Sharma DK, Short V, Somannavar MS, Wallace D, Shah H, Singh M, Askari S, Bellad MB. RAPIDIRON: Reducing Anaemia in Pregnancy in India-a 3-arm, randomized-controlled trial comparing the effectiveness of oral iron with single-dose intravenous iron in the treatment of iron deficiency anaemia in pregnant women and reducing low birth weight deliveries. Trials. 2021 Sep 23; 22(1):649. PMID: 34556166.
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    27. Boelig RC, Aagaard KM, Debbink MP, Shamshirsaz AA. Society for Maternal-Fetal Medicine Special Statement: COVID-19 research in pregnancy: progress and potential. Am J Obstet Gynecol. 2021 Sep 03. PMID: 34481778.
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    28. Boelig RC. Should singleton gestations without prior preterm birth receive an ultrasound-indicated cerclage? Tempting, but we must wait for more level 1 data. Am J Obstet Gynecol MFM. 2021 09; 3(5):100431. PMID: 34419385.
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    29. Garcia SM, Kellom KS, Boelig RC, Wang X, Matone M. Patient and Provider Perspectives on Acceptability, Access, and Adherence to 17-Alpha-Hydroxyprogesterone Caproate for Preterm Birth Prevention. Womens Health Rep (New Rochelle). 2021; 2(1):295-304. PMID: 34327511.
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    30. Boelig RC, Lam E, Rochani A, Kaushal G, Roman A, Kraft WK. Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one-time oral dosing in pregnancy. Clin Transl Sci. 2021 Jul 26. PMID: 34310083.
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    31. Boelig RC, Kripalu V, Chen SL, Cruz Y, Roman A, Berghella V. Utility of follow-up cervical length screening in low-risk women with a cervical length of 26 to 29 mm. Am J Obstet Gynecol. 2021 Feb 27. PMID: 33652056.
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    32. Smith J, Lafferty M, Boelig RC, Carola D, Adeniyi-Jones S, Kraft WK, Greenspan JS, Aghai ZH. Is Maternal Methadone Dose Associated with the Severity of Neonatal Abstinence Syndrome? Am J Perinatol. 2020 Dec 15. PMID: 33321531.
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    33. Roman A, Boelig R, Berghella V. 81 mg Aspirin: A Dosing Dilemma Response. Am J Obstet Gynecol. 2020 Dec 08. PMID: 33306966.
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    34. Roman A, Boelig R, Berghella V. Impact of aspirin on preeclampsia response. Am J Obstet Gynecol. 2020 Dec 08. PMID: 33306969.
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    35. Boelig RC, Wanees M, Zhan T, Berghella V, Roman A. Improving Utilization of Aspirin for Prevention of Preeclampsia in a High-Risk Urban Cohort: A Prospective Cohort Study. Am J Perinatol. 2020 Oct 24. PMID: 33099285.
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    36. Berghella V, Boelig R, Roman A, Burd J, Anderson K. Decreased incidence of preterm birth during coronavirus disease 2019 pandemic. Am J Obstet Gynecol MFM. 2020 11; 2(4):100258. PMID: 33083779.
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    37. Boelig RC, Lambert C, Pena JA, Stone J, Bernstein PS, Berghella V. Obstetric protocols in the setting of a pandemic. Semin Perinatol. 2020 Jul 24; 151295. PMID: 32829954.
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    38. Guo R, Neumann D, Lafferty M, Boelig R, Bell-Carey B, Edwards C, Greenspan JS, Derman R, Aghai ZH. Prevalence and Utility of Low Mean Corpuscular Volume in Infants Admitted to the Neonatal Intensive Care Unit. J Pediatr. 2020 Jul 21. PMID: 32702426.
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    39. Boelig RC, Bellussi F, Berghella V. Reply. Am J Obstet Gynecol MFM. 2020 Aug; 2(3):100158. PMID: 32838263.
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    40. Boelig RC. Let them eat! BJOG. 2020 May 25. PMID: 32449567.
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    41. Berghella V, Lesser T, Boelig RC, Roman A. Cervical length screening after 24 weeks for prediction and prevention of preterm birth: not evidence based yet…. Am J Obstet Gynecol MFM. 2020 May; 2(2):100097. PMID: 33345963.
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    42. Ward A, Greenberg V, Valcarcel B, Boelig RC, Al-Kouatly HB, Berghella V. Intramuscular progesterone in women with twins and a prior singleton spontaneous preterm birth. Am J Obstet Gynecol MFM. 2020 Aug; 2(3):100124. PMID: 33345870.
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    43. Boelig RC, Naert MN, Fox NS, Hennessy S, Chervoneva I, Berghella V, Roman A. Predictors of Early Preterm Birth Despite Vaginal Progesterone Therapy in Singletons with Short Cervix. Am J Perinatol. 2020 Apr 28. PMID: 32344443.
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    44. Boelig RC, Manuck T, Oliver EA, Di Mascio D, Saccone G, Bellussi F, Berghella V. Labor and delivery guidance for COVID-19. Am J Obstet Gynecol MFM. 2020 May; 2(2):100110. PMID: 32518901.
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    45. Boelig RC, Saccone G, Bellussi F, Berghella V. MFM guidance for COVID-19. Am J Obstet Gynecol MFM. 2020 Mar 19; 100106. PMID: 32363335.
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    46. Banala C, Moreno S, Cruz Y, Boelig RC, Saccone G, Berghella V, Schoen CN, Roman A. Impact of the ACOG guideline regarding low dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension. Am J Obstet Gynecol. 2020 Mar 12. PMID: 32173446.
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    47. Boelig RC, Zuppa AF, Kraft WK, Caritis S. Pharmacokinetics of Vaginal Progesterone in Pregnancy. Am J Obstet Gynecol. 2019 Jun 15. PMID: 31211965.
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    48. Boelig RC, Della Corte L, Ashoush S, McKenna D, Saccone G, Rajaram S, Berghella V. Oral progesterone for the prevention of recurrent preterm birth: systematic review and metaanalysis. Am J Obstet Gynecol MFM. 2019 03; 1(1):50-62. PMID: 31172132.
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    49. Boelig RC, Dugoff L, Roman A, Berghella V, Ludmir J. Predicting asymptomatic cervical dilation in pregnant patients with short mid-trimester cervical length: a secondary analysis of a randomized controlled trial. Acta Obstet Gynecol Scand. 2019 Jan 25. PMID: 30681719.
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    50. Boelig RC, Berghella V. What's new in preterm birth prediction and prevention? J Perinat Med. 2018 Jul 26; 46(5):455-456. PMID: 29794253.
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    51. Koot MH, Boelig RC, Van't Hooft J, Limpens J, Roseboom TJ, Painter RC, Grooten IJ. Variation in hyperemesis gravidarum definition and outcome reporting in randomised clinical trials: a systematic review. BJOG. 2018 Nov; 125(12):1514-1521. PMID: 29727913.
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    52. Boelig RC, Jiang E, Scheidemantle B, Villani M, Berghella V. Utilization of progesterone and cervical length screening for prevention of recurrent preterm birth. J Matern Fetal Neonatal Med. 2018 Jun 17; 1-8. PMID: 29792058.
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    53. Boelig RC, Villani M, Jiang E, Orzechowski KM, Berghella V. Prior Uterine Evacuation and the Risk of Short Cervical Length: A Retrospective Cohort Study. J Ultrasound Med. 2018 Jan 18. PMID: 29344987.
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    54. Navathe R, Saccone G, Villani M, Knapp J, Cruz Y, Boelig R, Roman A, Berghella V. Decrease in the incidence of threatened preterm labor after implementation of transvaginal ultrasound cervical length universal screening. J Matern Fetal Neonatal Med. 2018 Jan 05; 1-6. PMID: 29303014.
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    55. Boelig RC, Berghella V. Current options for mechanical prevention of preterm birth. Semin Perinatol. 2017 Dec; 41(8):452-460. PMID: 29033106.
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    56. Boelig RC. The dilemma of hyperemesis gravidarum: more answers, and more questions. Am J Clin Nutr. 2017 09; 106(3):711-712. PMID: 28768653.
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    57. Boelig RC. All That Is Left Unsaid. Obstet Gynecol. 2017 08; 130(2):377-378. PMID: 28697114.
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    58. Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, Berghella V. Interventions for treating hyperemesis gravidarum: A Cochrane systematic review and meta-analysis. J Matern Fetal Neonatal Med. 2017 Jun 14; 1-21. PMID: 28614956.
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    59. Boelig RC, Suhag A, Guarente J, Orzechowski K, Berghella V. Second-trimester cervical length and outcomes of induction of labor at term. J Matern Fetal Neonatal Med. 2017 Apr 10; 1-5. PMID: 28393580.
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    60. Boelig RC, Feltovich H, Spitz JL, Toland G, Berghella V, Iams JD. Assessment of Transvaginal Ultrasound Cervical Length Image Quality. Obstet Gynecol. 2017 Mar; 129(3):536-541. PMID: 28178045.
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    61. Orzechowski KM, Boelig RC, Berghella V. Cervical Length Screening in Asymptomatic Women at High Risk and Low Risk for Spontaneous Preterm Birth. Clin Obstet Gynecol. 2016 Jun; 59(2):241-51. PMID: 27015227.
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    62. Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, Berghella V. Interventions for treating hyperemesis gravidarum. Cochrane Database Syst Rev. 2016; 5:CD010607. PMID: 27168518.
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    63. Boelig RC, Orzechowski KM, Suhag A, Berghella V. Second trimester cervical length and prolonged pregnancy (.). J Matern Fetal Neonatal Med. 2016 Dec; 29(24):4088-91. PMID: 26952543.
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    64. Berghella V, Boelig RC. Always ask why! Am J Obstet Gynecol. 2016 Mar; 214(3):303-5. PMID: 26928144.
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    65. Boelig RC, Orzechowski KM, Berghella V. Cervical length, risk factors, and delivery outcomes among women with spontaneous preterm birth. J Matern Fetal Neonatal Med. 2016 Sep; 29(17):2840-4. PMID: 26452324.
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    66. Boelig RC, Coleman JS, Keller J, Sewell C, Anderson J. Preconception counseling and care in the setting of HIV: clinical characteristics and comorbidities. Infect Dis Obstet Gynecol. 2015; 2015:240613. PMID: 25838753.
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    67. Orzechowski KM, Boelig RC, Baxter JK, Berghella V. A universal transvaginal cervical length screening program for preterm birth prevention. Obstet Gynecol. 2014 Sep; 124(3):520-5. PMID: 25162252.
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    68. Orzechowski KM, Boelig R, Nicholas SS, Baxter J, Berghella V. Is universal cervical length screening indicated in women with prior term birth? Am J Obstet Gynecol. 2015 Feb; 212(2):234.e1-5. PMID: 25174798.
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    69. Vogell A, Boelig RC, Skora J, Baxter JK. Bilateral bell palsy as a presenting sign of preeclampsia. Obstet Gynecol. 2014 Aug; 124(2 Pt 2):459-61. PMID: 25004308.
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