Hristelina Ilieva

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentCenter For ALS
Address900 Walnut Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pinilla G, Kumar A, Floaters MK, Pardo CA, Rothstein J, Ilieva H. Increased synthesis of pro-inflammatory cytokines in C9ORF72 patients. Amyotroph Lateral Scler Frontotemporal Degener. 2021 Apr 30; 1-11. PMID: 33929933.
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    2. Ilieva HS, Newman JW, Fields RK, Croom JE. Valproic acid and zonisamide induced hyperammonemic encephalopathy. Clin Neurol Neurosurg. 2020 May 15; 196:105894. PMID: 32645624.
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    3. Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. Elife. 2019 Feb 12; 8. PMID: 30747709.
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    4. Ilieva H, Maragakis NJ. Motoneuron Disease: Clinical. Adv Neurobiol. 2017; 15:191-210. PMID: 28674982.
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    5. Ilieva H, Maragakis NJ. Motoneuron Disease: Basic Science. Adv Neurobiol. 2017; 15:163-190. PMID: 28674981.
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    6. Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, Jin S, Mancias P, Kiyama H, Yamanaka K. Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS. EMBO Mol Med. 2016 12; 8(12):1421-1437. PMID: 27821430.
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    7. Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS. Mol Ther. 2013 Dec; 21(12):2148-59. PMID: 24008656.
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    8. Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW. Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron. 2010 Aug 26; 67(4):575-87. PMID: 20797535.
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    9. Ilieva H, Polymenidou M, Cleveland DW. Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J Cell Biol. 2009 Dec 14; 187(6):761-72. PMID: 19951898.
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    10. Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J Clin Invest. 2009 Nov; 119(11):3437-49. PMID: 19841542.
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    11. Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12599-604. PMID: 18719118.
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    12. Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. PLoS One. 2008 Aug 06; 3(8):e2849. PMID: 18682740.
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    13. Nagata T, Ilieva H, Murakami T, Shiote M, Narai H, Ohta Y, Hayashi T, Shoji M, Abe K. Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis. Neurol Res. 2007 Dec; 29(8):767-71. PMID: 17672929.
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    14. Nagano I, Ilieva H, Shiote M, Murakami T, Yokoyama M, Shoji M, Abe K. Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis. J Neurol Sci. 2005 Aug 15; 235(1-2):61-8. PMID: 15990113.
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    15. Ilieva H, Nagano I, Murakami T, Shiote M, Shoji M, Abe K. Sustained induction of survival p-AKT and p-ERK signals after transient hypoxia in mice spinal cord with G93A mutant human SOD1 protein. J Neurol Sci. 2003 Nov 15; 215(1-2):57-62. PMID: 14568129.
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    16. Murakami T, Ilieva H, Shiote M, Nagata T, Nagano I, Shoji M, Abe K. Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene. Brain Res. 2003 Nov 07; 989(2):231-7. PMID: 14556945.
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    17. Ilieva HS, Nagano I, Murakami T, Shiote M, Manabe Y, Abe K. Age-related changes in peroxisomal membrane protein 70 and superoxide dismutase 1 in transgenic G93A mice. Neurol Res. 2003 Jun; 25(4):423-6. PMID: 12870272.
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    18. Ilieva H, Nagano I, Murakami T, Shiote M, Manabe Y, Abe K. Change in superoxide dismutase 1 protein localization towards mitochondria: an immunohistochemical study in transgenic G93A mice. Neurosci Lett. 2002 Oct 25; 332(1):53-6. PMID: 12377383.
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