S100 Calcium-Binding Protein A4
"S100 Calcium-Binding Protein A4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
| Descriptor ID |
D000071999
|
| MeSH Number(s) |
D12.776.157.125.750.813
|
| Concept/Terms |
S100 Calcium-Binding Protein A4- S100 Calcium-Binding Protein A4
- S100 Calcium Binding Protein A4
- Metastasin Protein
- Placental Calcium-Binding Protein
- Calcium-Binding Protein, Placental
- Placental Calcium Binding Protein
- Calvasculin Protein
- Fibroblast-Specific Protein 1
- Fibroblast Specific Protein 1
- S100A4 Protein
|
Below are MeSH descriptors whose meaning is more general than "S100 Calcium-Binding Protein A4".
Below are MeSH descriptors whose meaning is more specific than "S100 Calcium-Binding Protein A4".
This graph shows the total number of publications written about "S100 Calcium-Binding Protein A4" by people in this website by year, and whether "S100 Calcium-Binding Protein A4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "S100 Calcium-Binding Protein A4" by people in Profiles.
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Rasanen K, Sriswasdi S, Valiga A, Tang HY, Zhang G, Perego M, Somasundaram R, Li L, Speicher K, Klein-Szanto AJ, Basu D, Rustgi AK, Speicher DW, Herlyn M. Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target. Mol Cell Proteomics. 2013 Dec; 12(12):3778-92.
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Rosty C, Ueki T, Argani P, Jansen M, Yeo CJ, Cameron JL, Hruban RH, Goggins M. Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation. Am J Pathol. 2002 Jan; 160(1):45-50.