Myeloid Cell Leukemia Sequence 1 Protein
"Myeloid Cell Leukemia Sequence 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
| Descriptor ID |
D064549
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| MeSH Number(s) |
D12.644.360.075.718.984 D12.776.476.075.718.968 D12.776.624.664.700.169.500
|
| Concept/Terms |
Myeloid Cell Leukemia Sequence 1 Protein- Myeloid Cell Leukemia Sequence 1 Protein
- Myeloid Cell Leukemia Sequence 1
- Myeloid Cell Factor-1
- Cell Factor-1, Myeloid
- Factor-1, Myeloid Cell
- Myeloid Cell Factor 1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1
|
Below are MeSH descriptors whose meaning is more general than "Myeloid Cell Leukemia Sequence 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Cell Leukemia Sequence 1 Protein".
This graph shows the total number of publications written about "Myeloid Cell Leukemia Sequence 1 Protein" by people in this website by year, and whether "Myeloid Cell Leukemia Sequence 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloid Cell Leukemia Sequence 1 Protein" by people in Profiles.
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Kapoor S, Natarajan K, Baldwin PR, Doshi KA, Lapidus RG, Mathias TJ, Scarpa M, Trotta R, Davila E, Kraus M, Huszar D, Tron AE, Perrotti D, Baer MR. Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation. Clin Cancer Res. 2018 01 01; 24(1):234-247.
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Tsai AC, Pai HC, Wang CY, Liou JP, Teng CM, Wang JC, Pan SL. In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells. Br J Pharmacol. 2014 Jan; 171(1):122-33.