Glycogen Synthase Kinase 3 beta
"Glycogen Synthase Kinase 3 beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
Descriptor ID |
D000071679
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MeSH Number(s) |
D05.500.117.875.500 D08.811.913.696.620.682.700.429.500.500 D08.811.913.696.620.682.700.646.625.500 D12.644.360.300.500.500 D12.776.476.081.875.500 D12.776.476.300.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3 beta".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3 beta".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3 beta" by people in this website by year, and whether "Glycogen Synthase Kinase 3 beta" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 2 | 2 |
2007 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3 beta" by people in Profiles.
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Tymanskyj SR, Lin S, Gordon-Weeks PR. Evolution of the spatial distribution of MAP1B phosphorylation sites in vertebrate neurons. J Anat. 2010 Jun; 216(6):692-704.
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Korzick DH, Kostyak JC, Hunter JC, Saupe KW. Local delivery of PKCepsilon-activating peptide mimics ischemic preconditioning in aged hearts through GSK-3beta but not F1-ATPase inactivation. . 2007 Oct; 293(4):H2056-63.
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Hunter JC, Kostyak JC, Novotny JL, Simpson AM, Korzick DH. Estrogen deficiency decreases ischemic tolerance in the aged rat heart: Roles of PKCdelta, PKCepsilon, Akt, and GSK3beta. . 2007 Feb; 292(2):R800-9.
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Kostyak JC, Hunter JC, Korzick DH. Acute PKCdelta inhibition limits ischaemia-reperfusion injury in the aged rat heart: role of GSK-3beta. Cardiovasc Res. 2006 May 01; 70(2):325-34.