Clustered Regularly Interspaced Short Palindromic Repeats

"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.

Descriptor ID	D064112
MeSH Number(s)	G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
Concept/Terms	Clustered Regularly Interspaced Short Palindromic Repeats Clustered Regularly Interspaced Short Palindromic Repeats CRISPRs CRISPR CRISPR Sequences CRISPR Sequence Sequence, CRISPR Sequences, CRISPR Clustered Regularly Interspaced Short Palindromic Repeat CRISPR Elements CRISPR Element Element, CRISPR Elements, CRISPR CRISPR Spacers CRISPR Spacers CRISPR Spacer Spacer, CRISPR Spacers, CRISPR CRISPR Spacer Sequences CRISPR Spacer Sequence Sequence, CRISPR Spacer Sequences, CRISPR Spacer Spacer Sequence, CRISPR Spacer Sequences, CRISPR CRISPR-Cas Loci CRISPR-Cas Loci CRISPR Cas Loci CRISPR-Cas Locus Loci, CRISPR-Cas Locus, CRISPR-Cas CRISPR Loci CRISPR Loci Loci, CRISPR Locus, CRISPR CRISPR Clusters CRISPR Cluster Cluster, CRISPR Clusters, CRISPR CRISPR Locus CRISPR Arrays Array, CRISPR Arrays, CRISPR CRISPR Array

Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Base Sequence [G02.111.570.080]
Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
Tandem Repeat Sequences [G02.111.570.080.708.800]
Inverted Repeat Sequences [G02.111.570.080.708.800.325]
Clustered Regularly Interspaced Short Palindromic Repeats [G02.111.570.080.708.800.325.500]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Base Sequence [G05.360.080]
Repetitive Sequences, Nucleic Acid [G05.360.080.708]
Tandem Repeat Sequences [G05.360.080.708.800]
Inverted Repeat Sequences [G05.360.080.708.800.325]
Clustered Regularly Interspaced Short Palindromic Repeats [G05.360.080.708.800.325.500]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Tandem Repeat Sequences [G05.360.340.024.850]
Clustered Regularly Interspaced Short Palindromic Repeats [G05.360.340.024.850.069]

Below are MeSH descriptors whose meaning is related to "Clustered Regularly Interspaced Short Palindromic Repeats".

Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2017 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2017	1	1	2
2018	0	1	1
2019	1	0	1
2020	0	1	1
2021	0	2	2
2024	0	1	1

Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.

Ghahremani S, Kanwal A, Pettinato A, Ladha F, Legere N, Thakar K, Zhu Y, Tjong H, Wilderman A, Stump WT, Greenberg L, Greenberg MJ, Cotney J, Wei CL, Hinson JT. CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants. Circulation. 2024 Apr 16; 149(16):1285-1297.

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Montenont E, Bhatlekar S, Jacob S, Kosaka Y, Manne BK, Lee O, Parra-Izquierdo I, Tugolukova E, Tolley ND, Rondina MT, Bray PF, Rowley JW. CRISPR-edited megakaryocytes for rapid screening of platelet gene functions. Blood Adv. 2021 05 11; 5(9):2362-2374.

View in: PubMed
Cai J, Kropf E, Hou YM, Iacovitti L. A stress-free strategy to correct point mutations in patient iPS cells. Stem Cell Res. 2021 05; 53:102332.

View in: PubMed
Mitra R, Adams CM, Jiang W, Greenawalt E, Eischen CM. Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival. Nat Commun. 2020 02 20; 11(1):968.

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Simonneau C, Yang J, Kong X, Kilker R, Edelstein L, Fortina P, Londin E, Horowitz A. Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen. Sci Rep. 2019 Oct 02; 9(1):14238.

View in: PubMed
Mariscal AM, Kakizawa S, Hsu JY, Tanaka K, Gonz?lez-Gonz?lez L, Broto A, Querol E, Lluch-Senar M, Pi?ero-Lambea C, Sun L, Weyman PD, Wise KS, Merryman C, Tse G, Moore AJ, Hutchison CA, Smith HO, Tomita M, Venter JC, Glass JI, Pi?ol J, Suzuki Y. Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells. ACS Synth Biol. 2018 06 15; 7(6):1538-1552.

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Carpenter MR, Kalburge SS, Borowski JD, Peters MC, Colwell RR, Boyd EF. CRISPR-Cas and Contact-Dependent Secretion Systems Present on Excisable Pathogenicity Islands with Conserved Recombination Modules. J Bacteriol. 2017 05 15; 199(10).

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Lal S, Cheung EC, Zarei M, Preet R, Chand SN, Mambelli-Lisboa NC, Romeo C, Stout MC, Londin E, Goetz A, Lowder CY, Nevler A, Yeo CJ, Campbell PM, Winter JM, Dixon DA, Brody JR. CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype. Mol Cancer Res. 2017 06; 15(6):696-707.

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