alpha7 Nicotinic Acetylcholine Receptor
"alpha7 Nicotinic Acetylcholine Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric α7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen.
| Descriptor ID |
D064569
|
| MeSH Number(s) |
D12.776.157.530.400.400.100.500.500 D12.776.543.550.450.500.100.500.500 D12.776.543.585.400.500.100.500.500 D12.776.543.750.130.687.500 D12.776.543.750.720.360.550.500
|
| Concept/Terms |
Receptor, alpha-Bungarotoxin- Receptor, alpha-Bungarotoxin
- Receptor, alpha Bungarotoxin
- alpha-Bungarotoxin Receptor
- alpha-Bungarotoxin Receptors
- Receptors, alpha-Bungarotoxin
- alpha Bungarotoxin Receptors
|
Below are MeSH descriptors whose meaning is more general than "alpha7 Nicotinic Acetylcholine Receptor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.157.530.400.400.100.500.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.550.450.500.100.500.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.585.400.500.100.500.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.130.687.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
- alpha7 Nicotinic Acetylcholine Receptor [D12.776.543.750.720.360.550.500]
Below are MeSH descriptors whose meaning is more specific than "alpha7 Nicotinic Acetylcholine Receptor".
This graph shows the total number of publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in this website by year, and whether "alpha7 Nicotinic Acetylcholine Receptor" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "alpha7 Nicotinic Acetylcholine Receptor" by people in Profiles.
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Vicary GW, Ritzenthaler JD, Panchabhai TS, Torres-González E, Roman J. Nicotine stimulates collagen type I expression in lung via a7 nicotinic acetylcholine receptors. Respir Res. 2017 06 02; 18(1):115.
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Wongtrakool C, Wang N, Hyde DM, Roman J, Spindel ER. Prenatal nicotine exposure alters lung function and airway geometry through a7 nicotinic receptors. Am J Respir Cell Mol Biol. 2012 May; 46(5):695-702.
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Hruska M, Keefe J, Wert D, Tekinay AB, Hulce JJ, Ibañez-Tallon I, Nishi R. Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes alpha7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons. J Neurosci. 2009 Nov 25; 29(47):14847-54.
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Sun X, Ritzenthaler JD, Zhong X, Zheng Y, Roman J, Han S. Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha. Cancer Res. 2009 Aug 15; 69(16):6445-53.
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Hruska M, Nishi R. Cell-autonomous inhibition of alpha 7-containing nicotinic acetylcholine receptors prevents death of parasympathetic neurons during development. J Neurosci. 2007 Oct 24; 27(43):11501-9.
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Zheng Y, Ritzenthaler JD, Roman J, Han S. Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression. Am J Respir Cell Mol Biol. 2007 Dec; 37(6):681-90.
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Wongtrakool C, Roser-Page S, Rivera HN, Roman J. Nicotine alters lung branching morphogenesis through the alpha7 nicotinic acetylcholine receptor. Am J Physiol Lung Cell Mol Physiol. 2007 Sep; 293(3):L611-8.
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Roman J, Ritzenthaler JD, Bechara R, Brown LA, Guidot D. Ethanol stimulates the expression of fibronectin in lung fibroblasts via kinase-dependent signals that activate CREB. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L975-87.