Signaling Lymphocytic Activation Molecule Family Member 1
"Signaling Lymphocytic Activation Molecule Family Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
| Descriptor ID |
D000071177
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| MeSH Number(s) |
D12.776.395.550.736.500 D12.776.543.550.746.500 D12.776.543.750.705.970.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Family Member 1".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Family Member 1".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Family Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in Profiles.
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Naaman H, Rabinski T, Yizhak A, Mizrahi S, Avni YS, Taube R, Rager B, Weinstein Y, Rall G, Gopas J, Ofir R. Measles Virus Persistent Infection of Human Induced Pluripotent Stem Cells. Cell Reprogram. 2018 02; 20(1):17-26.
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Soni C, Domeier PP, Wong EB, Khan TN, Elias MJ, Schell SL, Lukacher AE, Cooper TK, Rahman ZS. Distinct and synergistic roles of Fc?RIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity. J Autoimmun. 2015 Sep; 63:31-46.
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Hu T, Gimferrer I, Simmons A, Wiest D, Alberola-Ila J. The Ras/MAPK pathway is required for generation of iNKT cells. PLoS One. 2011 May 10; 6(5):e19890.
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Markovic-Plese S, Cortese I, Wandinger KP, McFarland HF, Martin R. CD4+CD28- costimulation-independent T cells in multiple sclerosis. J Clin Invest. 2001 Oct; 108(8):1185-94.
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Manchester M, Rall GF. Model Systems: transgenic mouse models for measles pathogenesis. Trends Microbiol. 2001 Jan; 9(1):19-23.