Placenta Growth Factor

"Placenta Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

Descriptor ID	D000072483
MeSH Number(s)	D12.644.276.100.800.100 D12.776.780.551
Concept/Terms	Placenta Growth Factor Placenta Growth Factor Factor, Placenta Growth Growth Factor, Placenta Placenta Growth Factor, PLGF-1 Isoform Placenta Growth Factor, PLGF-1 Isoform Placenta Growth Factor, PLGF 1 Isoform Placenta Growth Factor, PLGF-3 Isoform Placenta Growth Factor, PLGF-3 Isoform Placenta Growth Factor, PLGF 3 Isoform Placenta Growth Factor, PLGF-4 Isoform Placenta Growth Factor, PLGF-4 Isoform Placenta Growth Factor, PLGF 4 Isoform Placenta Growth Factor, PLGF-2 Isoform Placenta Growth Factor, PLGF-2 Isoform Placenta Growth Factor, PLGF 2 Isoform

Below are MeSH descriptors whose meaning is more general than "Placenta Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Angiogenic Proteins [D12.644.276.100]
Vascular Endothelial Growth Factors [D12.644.276.100.800]
Placenta Growth Factor [D12.644.276.100.800.100]
Proteins [D12.776]
Pregnancy Proteins [D12.776.780]
Placenta Growth Factor [D12.776.780.551]

Below are MeSH descriptors whose meaning is related to "Placenta Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Placenta Growth Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Placenta Growth Factor" by people in this website by year, and whether "Placenta Growth Factor" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 2000 and 2007 and 2008 and 2009 and 2010 and 2012 and 2013 and 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2007	0	1	1
2008	0	1	1
2009	0	1	1
2010	0	1	1
2012	0	1	1
2013	0	1	1
2019	1	0	1
2022	0	1	1

Below are the most recent publications written about "Placenta Growth Factor" by people in Profiles.

Kastora SL, Pana TA, Sarwar Y, Myint PK, Mamas MA. Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis. Mol Diagn Ther. 2022 07; 26(4):369-382.

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Duran EK, Cook NR, Bobadilla M, Kim E, Manson JE, Buring JE, Ridker PM, Pradhan AD. Plasma Placental Growth Factor Concentrations Are Elevated Well in Advance of Type 2 Diabetes Mellitus Onset: Prospective Data From the WHS. J Am Heart Assoc. 2019 08 06; 8(15):e012790.

View in: PubMed
Myatt L, Clifton RG, Roberts JM, Spong CY, Wapner RJ, Thorp JM, Mercer BM, Peaceman AM, Ramin SM, Carpenter MW, Sciscione A, Tolosa JE, Saade G, Sorokin Y, Anderson GD. Can changes in angiogenic biomarkers between the first and second trimesters of pregnancy predict development of pre-eclampsia in a low-risk nulliparous patient population? BJOG. 2013 Sep; 120(10):1183-91.

View in: PubMed
Myatt L, Clifton RG, Roberts JM, Spong CY, Hauth JC, Varner MW, Thorp JM, Mercer BM, Peaceman AM, Ramin SM, Carpenter MW, Iams JD, Sciscione A, Harper M, Tolosa JE, Saade G, Sorokin Y, Anderson GD. First-trimester prediction of preeclampsia in nulliparous women at low risk. Obstet Gynecol. 2012 Jun; 119(6):1234-42.

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Maynard SE, Moore Simas TA, Bur L, Crawford SL, Solitro MJ, Meyer BA. Soluble endoglin for the prediction of preeclampsia in a high risk cohort. Hypertens Pregnancy. 2010; 29(3):330-41.

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Zhang P, Baxter J, Vinod K, Tulenko TN, Di Muzio PJ. Endothelial differentiation of amniotic fluid-derived stem cells: synergism of biochemical and shear force stimuli. Stem Cells Dev. 2009 Nov; 18(9):1299-308.

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Maynard SE, Moore Simas TA, Solitro MJ, Rajan A, Crawford S, Soderland P, Meyer BA. Circulating angiogenic factors in singleton vs multiple-gestation pregnancies. Am J Obstet Gynecol. 2008 Feb; 198(2):200.e1-7.

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Moore Simas TA, Crawford SL, Solitro MJ, Frost SC, Meyer BA, Maynard SE. Angiogenic factors for the prediction of preeclampsia in high-risk women. Am J Obstet Gynecol. 2007 Sep; 197(3):244.e1-8.

View in: PubMed
Graeven U, Rodeck U, Karpinski S, Jost M, Andre N, Schmiegel W. Expression patterns of placenta growth factor in human melanocytic cell lines. J Invest Dermatol. 2000 Jul; 115(1):118-23.

View in: PubMed

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