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Adam Bailis

TitleAssoc Dean
InstitutionThomas Jefferson University
DepartmentJSHP - Office of the Dean
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    F32GM012079     (BAILIS, ADAM M)Mar 14, 1988
    NIH/NIGMS
    THE GENETIC CONTROL OF MITOTIC RECOMBINATION IN YEAST
    Role: Principal Investigator

    R01GM057484     (BAILIS, ADAM M)May 1, 1998 - Apr 30, 2008
    NIH/NIGMS
    Genome stability in rad mutants
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Alissa D. Clear, Glenn M. Manthey, Olivia Lewis, Isabelle Y. Lopez, Rossana Rico, Shannon Owens, M. Cristina Negritto, Elise W. Wolf, Jason Xu, Nikola Kenjic, J. Jefferson P. Perry, Aaron W. Adamson, Susan L. Neuhausen, Adam M. Bailis. Variants of the human RAD52 gene confer defects in ionizing radiation resistance and homologous recombination repair in budding yeast. Microbial Cell. 2020; 7(10):270-285.
    2. Clear AD, Manthey GM, Lewis O, Lopez IY, Rico R, Owens S, Negritto MC, Wolf EW, Xu J, Kenjic N, Perry JJP, Adamson AW, Neuhausen SL, Bailis AM. Variants of the human RAD52 gene confer defects in ionizing radiation resistance and homologous recombination repair in budding yeast. Microb Cell. 2020 Jul 20; 7(10):270-285. PMID: 33015141.
      View in: PubMed
    3. Adamson AW, Ding YC, Mendez-Dorantes C, Bailis AM, Stark JM, Neuhausen SL. The RAD52-S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations. Mol Oncol. 2020 Mar 16. PMID: 32175645.
      View in: PubMed
    4. Ding YC, Adamson AW, Steele L, Bailis AM, John EM, Tomlinson G, Neuhausen SL. Discovery of mutations in homologous recombination genes in African-American women with breast cancer. Fam Cancer. 2018 04; 17(2):187-195. PMID: 28864920.
      View in: PubMed
    5. Manthey GM, Clear AD, Liddell LC, Negritto MC, Bailis AM. Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair. Nucleic Acids Res. 2017 02 28; 45(4):1879-1888. PMID: 27923995.
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    6. Liddell LC, Manthey GM, Owens SN, Fu BX, Bailis AM. Alleles of the homologous recombination gene, RAD59, identify multiple responses to disrupted DNA replication in Saccharomyces cerevisiae. BMC Microbiol. 2013 Oct 14; 13:229. PMID: 24125552.
      View in: PubMed
    7. Pannunzio NR, Manthey GM, Liddell LC, Fu BX, Roberts CM, Bailis AM. Rad59 regulates association of Rad52 with DNA double-strand breaks. Microbiologyopen. 2012 Sep; 1(3):285-97. PMID: 23170228.
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    8. Clague J, Wilhoite G, Adamson A, Bailis A, Weitzel JN, Neuhausen SL. RAD51C germline mutations in breast and ovarian cancer cases from high-risk families. PLoS One. 2011; 6(9):e25632. PMID: 21980511.
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    9. Liddell L, Manthey G, Pannunzio N, Bailis A. Quantitation and analysis of the formation of HO-endonuclease stimulated chromosomal translocations by single-strand annealing in Saccharomyces cerevisiae. J Vis Exp. 2011 Sep 23; (55). PMID: 21968396.
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    10. Manthey GM, Bailis AM. Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae. PLoS One. 2010 Jul 29; 5(7):e11889. PMID: 20686691.
      View in: PubMed
    11. Pannunzio NR, Manthey GM, Bailis AM. RAD59 and RAD1 cooperate in translocation formation by single-strand annealing in Saccharomyces cerevisiae. Curr Genet. 2010 Feb; 56(1):87-100. PMID: 20012294.
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    12. Manthey GM, Naik N, Bailis AM. Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae. PLoS One. 2009 Oct 16; 4(10):e7488. PMID: 19834615.
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    13. Meyer DH, Bailis AM. Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae. PLoS One. 2008 Oct 02; 3(10):e3318. PMID: 18830407.
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    14. Mito E, Mokhnatkin JV, Steele MC, Buettner VL, Sommer SS, Manthey GM, Bailis AM. Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae. Genetics. 2008 Aug; 179(4):1795-806. PMID: 18711219.
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    15. Meyer DH, Bailis AM. Mating type influences chromosome loss and replicative senescence in telomerase-deficient budding yeast by Dnl4-dependent telomere fusion. Mol Microbiol. 2008 Sep; 69(5):1246-54. PMID: 18627461.
      View in: PubMed
    16. Pannunzio NR, Manthey GM, Bailis AM. RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiae. DNA Repair (Amst). 2008 May 03; 7(5):788-800. PMID: 18373960.
      View in: PubMed
    17. Navarro MS, Bi L, Bailis AM. A mutant allele of the transcription factor IIH helicase gene, RAD3, promotes loss of heterozygosity in response to a DNA replication defect in Saccharomyces cerevisiae. Genetics. 2007 Jul; 176(3):1391-402. PMID: 17483411.
      View in: PubMed
    18. Meyer DH, Bailis AM. Telomere dysfunction drives increased mutation by error-prone polymerases Rev1 and zeta in Saccharomyces cerevisiae. Genetics. 2007 Mar; 175(3):1533-7. PMID: 17151233.
      View in: PubMed
    19. Manthey GM, Navarro MS, Bailis AM. DNA fragment transplacement in Saccharomyces cerevisiae: some genetic considerations. Methods Mol Biol. 2004; 262:157-72. PMID: 14769961.
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    20. Manthey GM, Bailis AM. Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol. 2002 Aug; 22(15):5347-56. PMID: 12101230.
      View in: PubMed
    21. Garfinkel DJ, Bailis AM. Nucleotide Excision Repair, Genome Stability, and Human Disease: New Insight from Model Systems. J Biomed Biotechnol. 2002; 2(2):55-60. PMID: 12488584.
      View in: PubMed
    22. Negritto MC, Qiu J, Ratay DO, Shen B, Bailis AM. Novel function of Rad27 (FEN-1) in restricting short-sequence recombination. Mol Cell Biol. 2001 Apr; 21(7):2349-58. PMID: 11259584.
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    23. Lee BS, Bi L, Garfinkel DJ, Bailis AM. Nucleotide excision repair/TFIIH helicases RAD3 and SSL2 inhibit short-sequence recombination and Ty1 retrotransposition by similar mechanisms. Mol Cell Biol. 2000 Apr; 20(7):2436-45. PMID: 10713167.
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    24. Maines S, Negritto MC, Wu X, Manthey GM, Bailis AM. Novel mutations in the RAD3 and SSL1 genes perturb genome stability by stimulating recombination between short repeats in Saccharomyces cerevisiae. Genetics. 1998 Nov; 150(3):963-76. PMID: 9799251.
      View in: PubMed
    25. Qiu J, Guan MX, Bailis AM, Shen B. Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res. 1998 Jul 01; 26(13):3077-83. PMID: 9628902.
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    26. Negritto MT, Wu X, Kuo T, Chu S, Bailis AM. Influence of DNA sequence identity on efficiency of targeted gene replacement. Mol Cell Biol. 1997 Jan; 17(1):278-86. PMID: 8972208.
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    27. Bailis AM, Maines S. Nucleotide excision repair gene function in short-sequence recombination. J Bacteriol. 1996 Apr; 178(7):2136-40. PMID: 8606195.
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    28. Bailis AM, Maines S, Negritto MT. The essential helicase gene RAD3 suppresses short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol. 1995 Aug; 15(8):3998-4008. PMID: 7623796.
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    29. Bailis AM, Arthur L, Rothstein R. Genome rearrangement in top3 mutants of Saccharomyces cerevisiae requires a functional RAD1 excision repair gene. Mol Cell Biol. 1992 Nov; 12(11):4988-93. PMID: 1328869.
      View in: PubMed
    30. Bailis AM, Lopes JM, Kohlwein SD, Henry SA. Cis and trans regulatory elements required for regulation of the CHO1 gene of Saccharomyces cerevisiae. Nucleic Acids Res. 1992 Mar 25; 20(6):1411-8. PMID: 1313970.
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    31. Bailis AM, Rothstein R. A defect in mismatch repair in Saccharomyces cerevisiae stimulates ectopic recombination between homeologous genes by an excision repair dependent process. Genetics. 1990 Nov; 126(3):535-47. PMID: 2249754.
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    32. Sperka-Gottlieb C, Fasch EV, Kuchler K, Bailis AM, Henry SA, Paltauf F, Kohlwein SD. The hydrophilic and acidic N-terminus of the integral membrane enzyme phosphatidylserine synthase is required for efficient membrane insertion. Yeast. 1990 Jul-Aug; 6(4):331-43. PMID: 2168611.
      View in: PubMed
    33. Kelley MJ, Bailis AM, Henry SA, Carman GM. Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by inositol. Inositol is an inhibitor of phosphatidylserine synthase activity. Journal of Biological Chemistry. 1988; 263(34):18078-18085.
    34. Homann MJ, Bailis AM, Henry SA, Carman GM. Coordinate regulation of phospholipid biosynthesis by serine in Saccharomyces cerevisiae. J Bacteriol. 1987 Jul; 169(7):3276-80. PMID: 3036783.
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    35. Bailis AM, Poole MA, Carman GM, Henry SA. The membrane-associated enzyme phosphatidylserine synthase is regulated at the level of mRNA abundance. Molecular and Cellular Biology. 1987; 7(1):167-176.
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