"4-Nitroquinoline-1-oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
| Descriptor ID |
D015112
|
| MeSH Number(s) |
D02.640.820.600 D03.633.100.810.470.450 D03.661.243.500
|
| Concept/Terms |
4-Nitroquinoline-1-oxide- 4-Nitroquinoline-1-oxide
- 4 Nitroquinoline 1 oxide
- 4-Nitroquinoline-N-oxide
- 4 Nitroquinoline N oxide
|
Below are MeSH descriptors whose meaning is more general than "4-Nitroquinoline-1-oxide".
Below are MeSH descriptors whose meaning is more specific than "4-Nitroquinoline-1-oxide".
This graph shows the total number of publications written about "4-Nitroquinoline-1-oxide" by people in this website by year, and whether "4-Nitroquinoline-1-oxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "4-Nitroquinoline-1-oxide" by people in Profiles.
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Fong LY, Jiang Y, Rawahneh ML, Smalley KJ, Croce CM, Farber JL, Huebner K. Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis. Carcinogenesis. 2011 Apr; 32(4):554-60.
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Wan SG, Taccioli C, Jiang Y, Chen H, Smalley KJ, Huang K, Liu XP, Farber JL, Croce CM, Fong LY. Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer. 2011 Jul 15; 129(2):331-45.
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Fong LY, Jiang Y, Farber JL. Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. Carcinogenesis. 2006 Jul; 27(7):1489-96.
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Liu CG, Zhang L, Jiang Y, Chatterjee D, Croce CM, Huebner K, Fong LY. Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. Cancer Res. 2005 Sep 1; 65(17):7790-9.
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Fong LY, Zhang L, Jiang Y, Farber JL. Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. J Natl Cancer Inst. 2005 Jan 5; 97(1):40-50.
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Tamura I, Sakaki T, Chaqour B, Howard PS, Ikeo T, Macarak EJ. Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide. Oral Oncol. 2003 Jul; 39(5):506-14.