"Ofloxacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
| Descriptor ID |
D015242
|
| MeSH Number(s) |
D03.633.100.810.835.322.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ofloxacin".
Below are MeSH descriptors whose meaning is more specific than "Ofloxacin".
This graph shows the total number of publications written about "Ofloxacin" by people in this website by year, and whether "Ofloxacin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 0 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ofloxacin" by people in Profiles.
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Milder E, Vander J, Shah C, Garg S. Changes in antibiotic resistance patterns of conjunctival flora due to repeated use of topical antibiotics after intravitreal injection. Ophthalmology. 2012 Jul; 119(7):1420-4.
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George JM, Fiscella R, Blair M, Rodvold K, Ulanski L, Stokes J, Blair N, Pontiggia L. Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration. J Ocul Pharmacol Ther. 2010 Dec; 26(6):579-86.
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Hess G, Hill JW, Raut MK, Fisher AC, Mody S, Schein JR, Chen CC. Comparative antibiotic failure rates in the treatment of community-acquired pneumonia: Results from a claims analysis. Adv Ther. 2010 Oct; 27(10):743-55.
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Davies TA, Yee YC, Bush K, Sahm D, Evangelista A, Goldschmidt R. Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae. Microb Drug Resist. 2008 Sep; 14(3):187-96.
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Davies TA, Yee YC, Goldschmidt R, Sahm DF, Evangelista AT. Decline in the prevalence of pandemic clones Spain23F-1 and Spain9V-3 among US fluoroquinolone-resistant Streptococcus pneumoniae TRUST Surveillance isolates since 2001. Postgrad Med. 2008 Sep; 120(3 Suppl 1):39-45.
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Takahashi-Nishioka T, Yokogawa K, Tomatsu S, Nomura M, Kobayashi S, Miyamoto K. Targeted drug delivery to bone: pharmacokinetic and pharmacological properties of acidic oligopeptide-tagged drugs. Curr Drug Discov Technol. 2008 Mar; 5(1):39-48.
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Sahm DF, Benninger MS, Evangelista AT, Yee YC, Thornsberry C, Brown NP. Antimicrobial resistance trends among sinus isolates of Streptococcus pneumoniae in the United States (2001-2005). Otolaryngol Head Neck Surg. 2007 Mar; 136(3):385-9.
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Colyer MH, Weber ED, Weichel ED, Dick JS, Bower KS, Ward TP, Haller JA. Delayed intraocular foreign body removal without endophthalmitis during Operations Iraqi Freedom and Enduring Freedom. Ophthalmology. 2007 Aug; 114(8):1439-47.
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Davies TA, Yee YC, Goldschmidt R, Bush K, Sahm DF, Evangelista A. Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003). J Antimicrob Chemother. 2006 Mar; 57(3):437-42.
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Makaryus AN, Byrns K, Makaryus MN, Natarajan U, Singer C, Goldner B. Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event? South Med J. 2006 Jan; 99(1):52-6.