"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
| Descriptor ID |
D015342
|
| MeSH Number(s) |
D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
|
| Concept/Terms |
DNA Probes- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
|
Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
This graph shows the total number of publications written about "DNA Probes" by people in this website by year, and whether "DNA Probes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 1 | 4 | 5 |
| 1997 | 0 | 4 | 4 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "DNA Probes" by people in Profiles.
-
Gao Z, Xia H, Zauberman J, Tomaiuolo M, Ping J, Zhang Q, Ducos P, Ye H, Wang S, Yang X, Lubna F, Luo Z, Ren L, Johnson ATC. Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field-Effect Biosensors. Nano Lett. 2018 06 13; 18(6):3509-3515.
-
Sundaravaradan V, Mehta R, Harris DT, Zack JA, Ahmad N. Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells. Virology. 2010 Apr 25; 400(1):32-43.
-
Kricka LJ, Fortina P. Analytical ancestry: "firsts" in fluorescent labeling of nucleosides, nucleotides, and nucleic acids. Clin Chem. 2009 Apr; 55(4):670-83.
-
Gamper HB, Arar K, Gewirtz A, Hou YM. Unrestricted hybridization of oligonucleotides to structure-free DNA. Biochemistry. 2006 Jun 6; 45(22):6978-86.
-
Chen X, Pascal J, Vijayakumar S, Wilson GM, Ellenberger T, Tomkinson AE. Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes. Methods Enzymol. 2006; 409:39-52.
-
Gamper HB, Gewirtz A, Edwards J, Hou YM. Modified bases in RNA reduce secondary structure and enhance hybridization. Biochemistry. 2004 Aug 10; 43(31):10224-36.
-
Singh S, Zheng JJ, Peiper SC, Mclaughlin BJ. Gene expression profile of ARPE-19 during repair of the monolayer. Graefes Arch Clin Exp Ophthalmol. 2001 Dec; 239(12):946-51.
-
Tamura I, Rosenbloom J, Macarak E, Chaqour B. Regulation of Cyr61 gene expression by mechanical stretch through multiple signaling pathways. Am J Physiol Cell Physiol. 2001 Nov; 281(5):C1524-32.
-
Fortina P, Delgrosso K, Sakazume T, Santacroce R, Moutereau S, Su HJ, Graves D, McKenzie S, Surrey S. Simple two-color array-based approach for mutation detection. Eur J Hum Genet. 2000 Nov; 8(11):884-94.
-
Igoucheva O, Peritz AE, Levy D, Yoon K. A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system. Gene Ther. 1999 Dec; 6(12):1960-71.