"5'-Nucleotidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.
| Descriptor ID |
D015720
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| MeSH Number(s) |
D08.811.277.352.650.600.600
|
| Concept/Terms |
5'-Nucleotidase- 5'-Nucleotidase
- 5' Nucleotidase
- 5'-Nucleotidase Phosphoribolase
- 5' Nucleotidase Phosphoribolase
- Adenylate Phosphatase
- AMP Phosphatase
- Cytidylate Phosphatase
- Ecto-5'-Nucleotidase
- Ecto 5' Nucleotidase
- IMP Nucleotidase
- CD73 Antigens
- IMPase
- Inosinate Phosphatase
- Pyrimidine 5'-Nucleotidase
- Pyrimidine 5' Nucleotidase
- Thymidine Phosphatase
- Uridylate 5'-Nucleotidase
- Uridylate 5' Nucleotidase
- Antigen, CD73
- CD73 Antigen
- Antigens, CD73
- 5'-AMP Nucleotidase
- 5' AMP Nucleotidase
- IMP Phosphatase
|
Below are MeSH descriptors whose meaning is more general than "5'-Nucleotidase".
Below are MeSH descriptors whose meaning is more specific than "5'-Nucleotidase".
This graph shows the total number of publications written about "5'-Nucleotidase" by people in this website by year, and whether "5'-Nucleotidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "5'-Nucleotidase" by people in Profiles.
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Cudrici CD, Newman KA, Ferrante EA, Huffstutler R, Carney K, Betancourt B, Miettinen M, Siegel R, Katz JD, Nesti LJ, St Hilaire C, Lakshmipathy D, Wen H, Bagheri MH, Boehm M, Brofferio A. Multifocal calcific periarthritis with distinctive clinical and radiological features in patients with CD73 deficiency. Rheumatology (Oxford). 2021 12 24; 61(1):163-173.
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In TSH, Trotman-Grant A, Fahl S, Chen ELY, Zarin P, Moore AJ, Wiest DL, Z??iga-Pfl?cker JC, Anderson MK. HEB is required for the specification of fetal IL-17-producing ?d T cells. Nat Commun. 2017 12 08; 8(1):2004.
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Straussberg R, Onoufriadis A, Konen O, Zouabi Y, Cohen L, Lee JYW, Hsu CK, Simpson MA, McGrath JA. Novel homozygous missense mutation in NT5C2 underlying hereditary spastic paraplegia SPG45. Am J Med Genet A. 2017 Nov; 173(11):3109-3113.
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Cs?ka B, N?meth ZH, T?ro G, Koscs? B, K?kai E, Robson SC, Enjyoji K, Rolandelli RH, Erd?lyi K, Pacher P, Hask? G. CD39 improves survival in microbial sepsis by attenuating systemic inflammation. FASEB J. 2015 Jan; 29(1):25-36.
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Coffey F, Lee SY, Buus TB, Lauritsen JP, Wong GW, Joachims ML, Thompson LF, Z??iga-Pfl?cker JC, Kappes DJ, Wiest DL. The TCR ligand-inducible expression of CD73 marks ?d lineage commitment and a metastable intermediate in effector specification. J Exp Med. 2014 Feb 10; 211(2):329-43.
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Hask? G, Cs?ka B, Koscs? B, Chandra R, Pacher P, Thompson LF, Deitch EA, Spolarics Z, Vir?g L, Gergely P, Rolandelli RH, N?meth ZH. Ecto-5'-nucleotidase (CD73) decreases mortality and organ injury in sepsis. J Immunol. 2011 Oct 15; 187(8):4256-67.
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Szabó Z, Váradi A, Li Q, Uitto J. ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum. Mol Genet Metab. 2011 Nov; 104(3):421; author reply 422.