"4-Aminopyridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes.
| Descriptor ID |
D015761
|
| MeSH Number(s) |
D02.092.080.060 D03.383.725.050.060
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "4-Aminopyridine".
Below are MeSH descriptors whose meaning is more specific than "4-Aminopyridine".
This graph shows the total number of publications written about "4-Aminopyridine" by people in this website by year, and whether "4-Aminopyridine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "4-Aminopyridine" by people in Profiles.
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Moster ML, Sergott RC, Leiby BE. Dalfampridine Treatment in Nonarteritic Anterior Ischemic Optic Neuropathy. J Neuroophthalmol. 2017 09; 37(3):348-349.
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Chan KY, Chang RS, Lau VW, Chan ML, Lai T. Palliative care for a patient with Lambert-Eaton myasthenic syndrome: role of 3,4-diaminopyridine. Ann Palliat Med. 2016 Oct; 5(4):311-314.
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Burashnikov A, Antzelevitch C. Can inhibition of IKur promote atrial fibrillation? Heart Rhythm. 2008 Sep; 5(9):1304-9.
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Yan GX, Joshi A, Guo D, Hlaing T, Martin J, Xu X, Kowey PR. Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia. Circulation. 2004 Aug 31; 110(9):1036-41.
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Ramakers GM, Pasinelli P, van Beest M, van der Slot A, Gispen WH, De Graan PN. Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 field of the hippocampus. Neurosci Lett. 2000 May 26; 286(1):53-6.
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Donovan WH, Halter JA, Graves DE, Blight AR, Calvillo O, McCann MT, Sherwood AM, Castillo T, Parsons KC, Strayer JR. Intravenous infusion of 4-AP in chronic spinal cord injured subjects. Spinal Cord. 2000 Jan; 38(1):7-15.
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Jerng HH, Shahidullah M, Covarrubias M. Inactivation gating of Kv4 potassium channels: molecular interactions involving the inner vestibule of the pore. J Gen Physiol. 1999 May; 113(5):641-60.
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Yan GX, Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation. 1998 Nov 03; 98(18):1928-36.
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Zygmunt AC, Goodrow RJ, Antzelevitch C. Sodium effects on 4-aminopyridine-sensitive transient outward current in canine ventricular cells. Am J Physiol. 1997 Jan; 272(1 Pt 2):H1-11.
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Di Diego JM, Sun ZQ, Antzelevitch C. I(to) and action potential notch are smaller in left vs. right canine ventricular epicardium. Am J Physiol. 1996 Aug; 271(2 Pt 2):H548-61.