"Carbapenems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.
| Descriptor ID |
D015780
|
| MeSH Number(s) |
D02.065.589.099.124 D03.633.100.300.124
|
| Concept/Terms |
Carbapenems- Carbapenems
- Antibiotics, Carbapenem
- Carbapenem Antibiotics
|
Below are MeSH descriptors whose meaning is more general than "Carbapenems".
Below are MeSH descriptors whose meaning is more specific than "Carbapenems".
This graph shows the total number of publications written about "Carbapenems" by people in this website by year, and whether "Carbapenems" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carbapenems" by people in Profiles.
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Sun Z, Su L, Cotroneo N, Critchley I, Pucci M, Jain A, Palzkill T. Evaluation of Tebipenem Hydrolysis by ?-Lactamases Prevalent in Complicated Urinary Tract Infections. Antimicrob Agents Chemother. 2022 05 17; 66(5):e0239621.
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Cotroneo N, Rubio A, Critchley IA, Pillar C, Pucci MJ. In Vitro and In Vivo Characterization of Tebipenem, an Oral Carbapenem. Antimicrob Agents Chemother. 2020 07 22; 64(8).
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Shafquat Y, Jabeen K, Farooqi J, Mehmood K, Irfan S, Hasan R, Zafar A. Antimicrobial susceptibility against metronidazole and carbapenem in clinical anaerobic isolates from Pakistan. Antimicrob Resist Infect Control. 2019; 8:99.
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Rubio A, Pucci MJ, Jain A. Characterization of SPR994, an Orally Available Carbapenem, with Activity Comparable to Intravenously Administered Carbapenems. ACS Infect Dis. 2018 10 12; 4(10):1436-1438.
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Jain A, Utley L, Parr TR, Zabawa T, Pucci MJ. Tebipenem, the first oral carbapenem antibiotic. Expert Rev Anti Infect Ther. 2018 07; 16(7):513-522.
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Khan E, Ejaz M, Zafar A, Jabeen K, Shakoor S, Inayat R, Hasan R. Increased isolation of ESBL producing Klebsiella pneumoniae with emergence of carbapenem resistant isolates in Pakistan: report from a tertiary care hospital. J Pak Med Assoc. 2010 Mar; 60(3):186-90.
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Wong BK, Sahly Y, Mistry G, Waldman S, Musson D, Majumdar A, Xu X, Yu S, Lin JH, Singh R, Holland S. Comparative disposition of [14C]ertapenem, a novel carbapenem antibiotic, in rat, monkey and man. Xenobiotica. 2004 Apr; 34(4):379-89.