Comorbidity

"Comorbidity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.

Descriptor ID	D015897
MeSH Number(s)	N05.715.350.225 N06.850.490.687
Concept/Terms	Comorbidity Comorbidity Comorbidities

Below are MeSH descriptors whose meaning is more general than "Comorbidity".

Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Epidemiologic Factors [N05.715.350]
Comorbidity [N05.715.350.225]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Factors [N06.850.490]
Comorbidity [N06.850.490.687]

Below are MeSH descriptors whose meaning is related to "Comorbidity".

Below are MeSH descriptors whose meaning is more specific than "Comorbidity".

Comorbidity
Multimorbidity

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Comorbidity" by people in this website by year, and whether "Comorbidity" was a major or minor topic of these publications.

Bar chart showing 839 publications over 31 distinct years, with a maximum of 53 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	5	5
1996	0	5	5
1997	0	6	6
1998	0	2	2
1999	0	3	3
2000	0	6	6
2001	0	8	8
2002	0	18	18
2003	0	20	20
2004	1	27	28
2005	0	29	29
2006	0	40	40
2007	1	42	43
2008	0	37	37
2009	0	45	45
2010	0	49	49
2011	0	40	40
2012	1	31	32
2013	0	36	36
2014	2	33	35
2015	1	46	47
2016	1	47	48
2017	0	47	47
2018	2	51	53
2019	1	43	44
2020	1	51	52
2021	0	33	33
2022	0	10	10
2023	0	5	5
2024	2	6	8
2025	0	5	5

Below are the most recent publications written about "Comorbidity" by people in Profiles.

Khalife MR, Villarin C, Ruiz JM, McClelland SA, Rabbo KA, Matthew Mahoney J, Scott RC, Hernan AE. Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins after Early Life Seizures. eNeuro. 2025 Mar; 12(3).

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Jiang RY, Rochart R, Chu I, Duka S, Vendrame M. The Lehigh Valley Health Network Narcolepsy Cohort: clinical and polysomnographic analysis of 304 cases. J Clin Sleep Med. 2025 Mar 01; 21(3):479-491.

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Wunker C, Kumar S, Hallowell P, Collings A, Loss L, Bansal V, Kushner B, Zoumpou T, Kindel TL, Overby DW, Chang J, Ayloo S, Sabour AF, Ghanem OM, Aleassa E, Reid A, Rodriguez N, Haskins IN, Hilton LR, Slater BJ, Palazzo F. Bariatric surgery and relevant comorbidities: a systematic review and meta-analysis. Surg Endosc. 2025 Mar; 39(3):1419-1448.

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Holley D, Brooks A, Hartz M, Rao S, Zaubler T. mHealth-Augmented Care for Reducing Depression Symptom Severity Among Patients With Chronic Pain: Exploratory, Retrospective Cohort Study. JMIR Mhealth Uhealth. 2025 Jan 10; 13:e52764.

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Lee GJ, Hode V, Georgieva T, Rau J, Dodick DW, Schwedt TJ, Neugebauer V, Porreca F, Navratilova E. Prolactin-induced sensitization of trigeminal nociceptors promotes migraine co-morbidity in endometriosis. Cephalalgia. 2025 Jan; 45(1):3331024241313378.

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Elsawwah JK, Flanagan JS, Stopper PB, Rolandelli RH, Nemeth ZH. Risk factors and outcomes of renal insufficiency after colectomy for diverticulitis. Tech Coloproctol. 2024 Dec 12; 29(1):18.

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Kumar SS, Wunker C, Collings A, Bansal V, Zampou T, Chang J, Rodriguez N, Sabour A, Hilton LR, Ghanem OM, Kushner BS, Loss LJ, Aleassa EM, Haskins IN, Ayloo S, Reid A, Overby DW, Hallowell P, Kindel TL, Slater BJ, Palazzo F. SAGES guidelines for the management of comorbidities relevant to metabolic and bariatric surgery. Surg Endosc. 2025 Jan; 39(1):1-10.

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Levey N, Chen N, Ditre J, Sylvia L, Mudgal C, Bhashyam A, Garg R, Ring D, Vranceanu AM, Bakhshaie J. A Web-Based Mind-Body Intervention to Improve Resilience Among Patients With Nontraumatic Painful Upper-Extremity Conditions and Comorbid Risky Substance Use: Protocol for a Mixed Methods Study. JMIR Res Protoc. 2024 Dec 09; 13:e64547.

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Ehrenthal DB, Wang Y, Kirby RS. Importance of Modifiable Factors to Infant Health in the Context of Prenatal Opioid Use Disorder. J Addict Med. 2025 Mar-Apr 01; 19(2):157-164.

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Alwafi H, Naser AY, Ashoor DS, Alsharif A, Aldhahir AM, Alghamdi SM, Alqarni AA, Alsaleh N, Samkari JA, Alsanosi SM, Alqahtani JS, Dairi MS, Hafiz W, Tashkandi M, Ashoor A, Badr OI. Prevalence and predictors of polypharmacy and comorbidities among patients with chronic obstructive pulmonary disease: a cross-sectional retrospective study in a tertiary hospital in Saudi Arabia. BMC Pulm Med. 2024 Sep 14; 24(1):453.

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