"Torsades de Pointes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant form of polymorphic ventricular tachycardia that is characterized by HEART RATE between 200 and 250 beats per minute, and QRS complexes with changing amplitude and twisting of the points. The term also describes the syndrome of tachycardia with prolonged ventricular repolarization, long QT intervals exceeding 500 milliseconds or BRADYCARDIA. Torsades de pointes may be self-limited or may progress to VENTRICULAR FIBRILLATION.
| Descriptor ID |
D016171
|
| MeSH Number(s) |
C14.280.067.845.940.700 C14.280.123.875.940.700 C23.550.073.845.940.700
|
| Concept/Terms |
Torsades de Pointes- Torsades de Pointes
- Pointes, Torsades de
- de Pointes, Torsades
- Torsade de Pointes
- Pointes, Torsade de
- de Pointes, Torsade
|
Below are MeSH descriptors whose meaning is more general than "Torsades de Pointes".
Below are MeSH descriptors whose meaning is more specific than "Torsades de Pointes".
This graph shows the total number of publications written about "Torsades de Pointes" by people in this website by year, and whether "Torsades de Pointes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 2 | 3 |
| 1999 | 3 | 2 | 5 |
| 2000 | 3 | 0 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 3 | 0 | 3 |
| 2004 | 5 | 1 | 6 |
| 2005 | 3 | 1 | 4 |
| 2006 | 1 | 2 | 3 |
| 2007 | 3 | 2 | 5 |
| 2008 | 3 | 2 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Torsades de Pointes" by people in Profiles.
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Qi D, Li W, Quan XQ, Gao Y, Wang J, Guo L, Zhao W, Liu T, Gao C, Yan GX. Alternating Early Afterdepolarizations Underlying Bradycardia-Dependent Macroscopic T Wave and Discordant Mechanical Alternans. Circ Arrhythm Electrophysiol. 2023 01; 16(1):e011453.
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Chu AF, Rajagopal G, Sarkar S. The missing link: Unlocking the power of cardiac rhythm monitoring device based QT interval detection. Pacing Clin Electrophysiol. 2022 Mar; 45(3):401-409.
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Liu T, Liu J, Lu HR, Li H, Gallacher DJ, Chaudhary K, Wang Y, Yan GX. Utility of Normalized TdP Score System in Drug Proarrhythmic Potential Assessment: A Blinded in vitro Study of CiPA Drugs. Clin Pharmacol Ther. 2021 06; 109(6):1606-1617.
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Stabenau HF, Shen C, Zimetbaum P, Buxton AE, Tereshchenko LG, Waks JW. Global electrical heterogeneity associated with drug-induced torsades de pointes. Heart Rhythm. 2021 01; 18(1):57-62.
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Liu G, Xue X, Gao C, Huang J, Qi D, Zhang Y, Dong JZ, Ma CS, Yan GX. Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation. J Am Heart Assoc. 2017 May 18; 6(5).
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Lu HR, Gallacher DJ, Yan GX. Assessment of drug-induced proarrhythmia: The importance of study design in the rabbit left ventricular wedge model. J Pharmacol Toxicol Methods. 2016 Sep-Oct; 81:151-60.
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Liu G, Liu T, Cohen D, Liu T, Yan GX. How to determine cardiac ion channels targeted by drugs using the isolated rabbit ventricular wedge model. J Pharmacol Toxicol Methods. 2016 Sep-Oct; 81:161-70.
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Mirijello A, Fuorlo M, Addolorato G, Landolfi R. 'Doctor, treat your patient, not your monitor!' Tremor-induced ECG artefacts mimicking torsades de pointes. BMJ Case Rep. 2014 May 08; 2014.
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Rao P, Kowey PR. Drug-induced long-QT syndrome and torsade de pointes: an underrated problem? Europace. 2014 Jan; 16(1):4-5.
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Lu HR, Yan GX, Gallacher DJ. A new biomarker--index of cardiac electrophysiological balance (iCEB)--plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs). J Pharmacol Toxicol Methods. 2013 Sep-Oct; 68(2):250-259.