"Gene Products, tax" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcriptional trans-acting proteins of the promoter elements found in the long terminal repeats (LTR) of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The tax (trans-activator x; x is undefined) proteins act by binding to enhancer elements in the LTR.
| Descriptor ID |
D016356
|
| MeSH Number(s) |
D12.776.624.664.520.750.480 D12.776.964.700.750.480 D12.776.964.775.750.480 D12.776.964.925.984.410
|
| Concept/Terms |
Gene Products, tax- Gene Products, tax
- p40 tax
- p40(tax)
- tax Gene Products
- tax Protein
- Transforming Antigen p40x
- Antigen p40x, Transforming
- p40x, Transforming Antigen
- Trans-Activator Protein p40(tax)
- Trans-Activator Protein p40(x)
- Trans-Activator Protein p40x
- Trans Activator Protein p40x
- p40x, Trans-Activator Protein
- Trans-Activator Protein pX
- Trans Activator Protein pX
- pX, Trans-Activator Protein
- Transactivator p40(tax)
- Transactivator Protein p40(x)
- Gene Product, tax
- tax Gene Product
- Trans-Activator Protein p40(lor)
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, tax".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Oncogene Proteins, Viral [D12.776.624.664.520]
- Retroviridae Proteins, Oncogenic [D12.776.624.664.520.750]
- Gene Products, tax [D12.776.624.664.520.750.480]
- Viral Proteins [D12.776.964]
- Oncogene Proteins, Viral [D12.776.964.700]
- Retroviridae Proteins, Oncogenic [D12.776.964.700.750]
- Gene Products, tax [D12.776.964.700.750.480]
- Retroviridae Proteins [D12.776.964.775]
- Retroviridae Proteins, Oncogenic [D12.776.964.775.750]
- Gene Products, tax [D12.776.964.775.750.480]
- Viral Regulatory and Accessory Proteins [D12.776.964.925]
- Trans-Activators [D12.776.964.925.984]
- Gene Products, tax [D12.776.964.925.984.410]
Below are MeSH descriptors whose meaning is more specific than "Gene Products, tax".
This graph shows the total number of publications written about "Gene Products, tax" by people in this website by year, and whether "Gene Products, tax" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gene Products, tax" by people in Profiles.
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Cheng J, Kydd AR, Nakase K, Noonan KM, Murakami A, Tao H, Dwyer M, Xu C, Zhu Q, Marasco WA. Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein. Blood. 2007 Sep 15; 110(6):2110-20.
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Arnulf B, Villemain A, Nicot C, Mordelet E, Charneau P, Kersual J, Zermati Y, Mauviel A, Bazarbachi A, Hermine O. Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis. Blood. 2002 Dec 01; 100(12):4129-38.
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Nagai M, Kubota R, Greten TF, Schneck JP, Leist TP, Jacobson S. Increased activated human T cell lymphotropic virus type I (HTLV-I) Tax11-19-specific memory and effector CD8+ cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis: correlation with HTLV-I provirus load. J Infect Dis. 2001 Jan 15; 183(2):197-205.
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Azimi N, Jacobson S, Leist T, Waldmann TA. Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor. J Immunol. 1999 Oct 01; 163(7):4064-72.
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Greten TF, Slansky JE, Kubota R, Soldan SS, Jaffee EM, Leist TP, Pardoll DM, Jacobson S, Schneck JP. Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7568-73.
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Kubota S, Siomi H, Hatanaka M, Pomerantz RJ. Cis/trans-activation of the interleukin-9 receptor gene in an HTLV-I-transformed human lymphocytic cell. Oncogene. 1996 Apr 04; 12(7):1441-7.