"Bone Marrow Purging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic BONE MARROW TRANSPLANTATION.
| Descriptor ID |
D016465
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| MeSH Number(s) |
E02.120.142
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bone Marrow Purging".
Below are MeSH descriptors whose meaning is more specific than "Bone Marrow Purging".
This graph shows the total number of publications written about "Bone Marrow Purging" by people in this website by year, and whether "Bone Marrow Purging" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Marrow Purging" by people in Profiles.
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Keever-Taylor CA, Passweg J, Kawanishi Y, Casper J, Flomenberg N, Baxter-Lowe LA. Association of donor-derived host-reactive cytolytic and helper T cells with outcome following alternative donor T cell-depleted bone marrow transplantation. Bone Marrow Transplant. 1997 May; 19(10):1001-9.
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Young JW, Papadopoulos EB, Cunningham I, Castro-Malaspina H, Flomenberg N, Carabasi MH, Gulati SC, Brochstein JA, Heller G, Black P, et al. T-cell-depleted allogeneic bone marrow transplantation in adults with acute nonlymphocytic leukemia in first remission. Blood. 1992 Jun 15; 79(12):3380-7.
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Collins NH, Carabasi MH, Bleau S, Jagiello C, Young JW, Castro-Malaspina H, Flomenberg N, Papadopoulos EB, Emanuel D, Gillio A, et al. New technology for the depletion of T cells from soybean lectin agglutinated, HLA-matched bone marrow grafts for leukemia: initial laboratory and clinical results. Prog Clin Biol Res. 1992; 377:427-39.