"Terfenadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Descriptor ID |
D016593
|
| MeSH Number(s) |
D02.455.426.559.389.115.800 D03.383.621.855
|
| Concept/Terms |
Terfenadine- Terfenadine
- Terfenidine
- alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
|
Below are MeSH descriptors whose meaning is more general than "Terfenadine".
Below are MeSH descriptors whose meaning is more specific than "Terfenadine".
This graph shows the total number of publications written about "Terfenadine" by people in this website by year, and whether "Terfenadine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Terfenadine" by people in Profiles.
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Fish JM, Welchons DR, Kim YS, Lee SH, Ho WK, Antzelevitch C. Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome. Circulation. 2006 Mar 21; 113(11):1393-400.
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Fish JM, Antzelevitch C. Role of sodium and calcium channel block in unmasking the Brugada syndrome. Heart Rhythm. 2004 Jul; 1(2):210-7.
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Fish JM, Antzelevitch C. Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes. J Electrocardiol. 2003; 36 Suppl:173-9.
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Di Diego JM, Cordeiro JM, Goodrow RJ, Fish JM, Zygmunt AC, P?rez GJ, Scornik FS, Antzelevitch C. Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males. Circulation. 2002 Oct 08; 106(15):2004-11.
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Kane GC, Lipsky JJ. Drug-grapefruit juice interactions. Mayo Clin Proc. 2000 Sep; 75(9):933-42.
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Feroze H, Suri R, Silverman DI. Torsades de pointes from terfenadine and sotalol given in combination. Pacing Clin Electrophysiol. 1996 Oct; 19(10):1519-21.
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Hey JA, Del Prado M, Cuss FM, Egan RW, Sherwood J, Lin CC, Kreutner W. Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Clin Exp Allergy. 1995 Oct; 25(10):974-84.