"Vinculin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.
| Descriptor ID |
D016596
|
| MeSH Number(s) |
D12.776.220.990
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vinculin".
Below are MeSH descriptors whose meaning is more specific than "Vinculin".
This graph shows the total number of publications written about "Vinculin" by people in this website by year, and whether "Vinculin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vinculin" by people in Profiles.
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Cocom-Chan B, Khakzad H, Konate M, Aguilar DI, Bello C, Valencia-Gallardo C, Zarrouk Y, Fattaccioli J, Mauviel A, Javelaud D, Tran Van Nhieu G. IpaA reveals distinct modes of vinculin activation during Shigella invasion and cell-matrix adhesion. Life Sci Alliance. 2024 Aug; 7(8).
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Sabatelli P, Pellegrini C, Faldini C, Merlini L. Cytoskeletal and extracellular matrix alterations in limb girdle muscular dystrophy 2I muscle fibers. Neurol India. 2012 Sep-Oct; 60(5):510-1.
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Eddinger TJ, Schiebout JD, Swartz DR. Adherens junction-associated protein distribution differs in smooth muscle tissue and acutely isolated cells. Am J Physiol Gastrointest Liver Physiol. 2007 Feb; 292(2):G684-97.
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Hamel M, Kanyi D, Cipolle MD, Lowe-Krentz L. Active stress kinases in proliferating endothelial cells associated with cytoskeletal structures. Endothelium. 2006 May-Jun; 13(3):157-70.
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Yao H, Dashner EJ, van Golen CM, van Golen KL. RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Oncogene. 2006 Apr 13; 25(16):2285-96.
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Eddinger TJ, Schiebout JD, Swartz DR. Smooth muscle adherens junctions associated proteins are stable at the cell periphery during relaxation and activation. Am J Physiol Cell Physiol. 2005 Dec; 289(6):C1379-87.
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Ferreira-Cornwell MC, Luo Y, Narula N, Lenox JM, Lieberman M, Radice GL. Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart. J Cell Sci. 2002 Apr 15; 115(Pt 8):1623-34.
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Shah AK, Sinha RK, Hickok NJ, Tuan RS. High-resolution morphometric analysis of human osteoblastic cell adhesion on clinically relevant orthopedic alloys. Bone. 1999 May; 24(5):499-506.