"Talin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.
| Descriptor ID |
D016608
|
| MeSH Number(s) |
D12.776.220.985
|
| Concept/Terms |
Talin- Talin
- Band 2 Protein
- Protein, Band 2
|
Below are MeSH descriptors whose meaning is more general than "Talin".
Below are MeSH descriptors whose meaning is more specific than "Talin".
This graph shows the total number of publications written about "Talin" by people in this website by year, and whether "Talin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Talin" by people in Profiles.
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Wang Y, Zhao L, Suzuki A, Lian L, Min SH, Wang Z, Litvinov RI, Stalker TJ, Yago T, Klopocki AG, Schmidtke DW, Yin H, Choi JK, McEver RP, Weisel JW, Hartwig JH, Abrams CS. Platelets lacking PIP5KI? have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion. Blood. 2013 Apr 04; 121(14):2743-52.
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Eddinger TJ, Schiebout JD, Swartz DR. Adherens junction-associated protein distribution differs in smooth muscle tissue and acutely isolated cells. Am J Physiol Gastrointest Liver Physiol. 2007 Feb; 292(2):G684-97.
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Eddinger TJ, Schiebout JD, Swartz DR. Smooth muscle adherens junctions associated proteins are stable at the cell periphery during relaxation and activation. Am J Physiol Cell Physiol. 2005 Dec; 289(6):C1379-87.