Primary Ovarian Insufficiency

"Primary Ovarian Insufficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.

Descriptor ID	D016649
MeSH Number(s)	C13.351.500.056.630.750 C19.391.630.750
Concept/Terms	Primary Ovarian Insufficiency Primary Ovarian Insufficiency Insufficiency, Primary Ovarian Ovarian Insufficiency, Primary Premature Ovarian Failure Ovarian Failure, Premature Hypergonadotropic Ovarian Failure, X-Linked Hypergonadotropic Ovarian Failure, X-Linked Hypergonadotropic Ovarian Failure, X Linked FMR1-Related Primary Ovarian Insufficiency FMR1 Related Primary Ovarian Insufficiency Premature Ovarian Failure, X-Linked Premature Ovarian Failure, X Linked X-Linked Hypergonadotropic Ovarian Failure X Linked Hypergonadotropic Ovarian Failure Fragile X-Associated Primary Ovarian Insufficiency Fragile X Associated Primary Ovarian Insufficiency Premature Ovarian Failure 1 Gonadotropin-Resistant Ovary Syndrome Gonadotropin-Resistant Ovary Syndrome Gonadotropin Resistant Ovary Syndrome Resistant Ovary Syndrome

Below are MeSH descriptors whose meaning is more general than "Primary Ovarian Insufficiency".

Diseases [C]
Female Urogenital Diseases and Pregnancy Complications [C13]
Female Urogenital Diseases [C13.351]
Genital Diseases, Female [C13.351.500]
Adnexal Diseases [C13.351.500.056]
Ovarian Diseases [C13.351.500.056.630]
Primary Ovarian Insufficiency [C13.351.500.056.630.750]
Endocrine System Diseases [C19]
Gonadal Disorders [C19.391]
Ovarian Diseases [C19.391.630]
Primary Ovarian Insufficiency [C19.391.630.750]

Below are MeSH descriptors whose meaning is related to "Primary Ovarian Insufficiency".

Below are MeSH descriptors whose meaning is more specific than "Primary Ovarian Insufficiency".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Primary Ovarian Insufficiency" by people in this website by year, and whether "Primary Ovarian Insufficiency" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 2 publications in 2004 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2004	2	2
2005	1	1
2006	1	1
2007	1	1
2008	1	1
2013	2	2
2020	1	1
2022	1	1

Below are the most recent publications written about "Primary Ovarian Insufficiency" by people in Profiles.

Singh A, Tripathi R, Gupta RK, Rashid R, Jha RK. Gonadotropin upregulates intraovarian calpains-1 and -2 during ovarian follicular recruitment in the SD rat model. Reprod Biol. 2024 Jun; 24(2):100862.

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Ubba V, Gupta RK, Hakim BA, Bora HK, Sachdev M, Tripathi R, Jha RK. PKC-?II is downregulated in the premature ovarian failure SD rat model. Reprod Biol. 2023 Jun; 23(2):100754.

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Tong ZB, Otsuka N, Tu W, Wei Q, DeCherney AH. P450 Side-Chain Cleavage Enzyme (P450-SCC) Is an Ovarian Autoantigen in a Mouse Model for Autoimmune Oophoritis. Reprod Sci. 2022 08; 29(8):2391-2400.

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Cakiroglu Y, Saltik A, Yuceturk A, Karaosmanoglu O, Kopuk SY, Scott RT, Tiras B, Seli E. Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency. Aging (Albany NY). 2020 06 05; 12(11):10211-10222.

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Kim HJ, Lee MH, Lee JE, Park S, Lee ES, Kang YJ, Shin HN, Kim SI, Lee JH, Im SA, Ahn SH, Lee KS, Sohn J, Kim S, Nam SJ, Han W. Oncologic Safety of Gonadotropin-Releasing Hormone Agonist for Ovarian Function Protection During Breast Cancer Chemotherapy. Clin Breast Cancer. 2018 10; 18(5):e1165-e1172.

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Portnoi MF, Dumargne MC, Rojo S, Witchel SF, Duncan AJ, Eozenou C, Bignon-Topalovic J, Yatsenko SA, Rajkovic A, Reyes-Mugica M, Almstrup K, Fusee L, Srivastava Y, Chantot-Bastaraud S, Hyon C, Louis-Sylvestre C, Validire P, de Malleray Pichard C, Ravel C, Christin-Maitre S, Brauner R, Rossetti R, Persani L, Charreau EH, Dain L, Chiauzzi VA, Mazen I, Rouba H, Schluth-Bolard C, MacGowan S, McLean WHI, Patin E, Rajpert-De Meyts E, Jauch R, Achermann JC, Siffroi JP, McElreavey K, Bashamboo A. Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies. Hum Mol Genet. 2018 04 01; 27(7):1228-1240.

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Harrison SM, Campbell IM, Keays M, Granberg CF, Villanueva C, Tannin G, Zinn AR, Castrillon DH, Shaw CA, Stankiewicz P, Baker LA. Screening and familial characterization of copy-number variations in NR5A1 in 46,XY disorders of sex development and premature ovarian failure. Am J Med Genet A. 2013 Oct; 161A(10):2487-94.

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Henry NL, Xia R, Banerjee M, Gersch C, McConnell D, Giacherio D, Schott AF, Pearlman M, Stearns V, Partridge AH, Hayes DF. Predictors of recovery of ovarian function during aromatase inhibitor therapy. Ann Oncol. 2013 Aug; 24(8):2011-6.

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Cizmeli C, Lobel M, Franasiak J, Pastore LM. Levels and associations among self-esteem, fertility distress, coping, and reaction to potentially being a genetic carrier in women with diminished ovarian reserve. Fertil Steril. 2013 Jun; 99(7):2037-44.e3.

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Brahma PK, Kallen CB. Ovarian hyperstimulation after a short course of an oral contraceptive in a patient with premature ovarian failure. Fertil Steril. 2008 Nov; 90(5):2004.e15-7.

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