"HIV Core Protein p24" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by ELISA and Western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines.
| Descriptor ID |
D016655
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| MeSH Number(s) |
D12.776.964.775.350.362.500 D12.776.964.775.562.750.500 D12.776.964.970.600.850.350.362.500 D23.050.327.520.300
|
| Concept/Terms |
HIV Core Protein p24- HIV Core Protein p24
- HIV gag Gene Product p24
- HIV Major Core Protein p24
- p24(HIV)
- HIV Protein p24
- p24, HIV Protein
- HTLV-III p24
- HTLV III p24
- p24, HTLV-III
- p24 protein, Human Immunodeficiency Virus
- gag Protein p24, HIV
- HIV p24 Antigen
- p24 Antigen, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Core Protein p24".
Below are MeSH descriptors whose meaning is more specific than "HIV Core Protein p24".
This graph shows the total number of publications written about "HIV Core Protein p24" by people in this website by year, and whether "HIV Core Protein p24" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "HIV Core Protein p24" by people in Profiles.
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Cragin L, Pan F, Peng S, Zenilman JM, Green J, Doucet C, Chalfin DB, de Lissovoy G. Cost-effectiveness of a fourth-generation combination immunoassay for human immunodeficiency virus (HIV) antibody and p24 antigen for the detection of HIV infections in the United States. HIV Clin Trials. 2012 Jan-Feb; 13(1):11-22.
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Spacek LA, Lutwama F, Shihab HM, Summerton J, Kamya MR, Ronald A, Laeyendecker O, Quinn TC, Mayanja-Kizza H. Diagnostic accuracy of ultrasensitive heat-denatured HIV-1 p24 antigen in non-B subtypes in Kampala, Uganda. Int J STD AIDS. 2011 Jun; 22(6):310-4.
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Cordelier P, Strayer DS. Using gene delivery to protect HIV-susceptible CNS cells: inhibiting HIV replication in microglia. Virus Res. 2006 Jun; 118(1-2):87-97.
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Norris PJ, Stone JD, Anikeeva N, Heitman JW, Wilson IC, Hirschkorn DF, Clark MJ, Moffett HF, Cameron TO, Sykulev Y, Stern LJ, Walker BD. Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope. Mol Immunol. 2006 Mar; 43(9):1349-57.
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Fang J, Kubota S, Yang B, Zhou N, Zhang H, Godbout R, Pomerantz RJ. A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev. Virology. 2004 Dec 20; 330(2):471-80.
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Cordelier P, Van Bockstaele E, Calarota SA, Strayer DS. Inhibiting AIDS in the central nervous system: gene delivery to protect neurons from HIV. Mol Ther. 2003 Jun; 7(6):801-10.
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Cordelier P, Calarota SA, Strayer DS. Trans-activated interferon-alpha2 delivered to T cells by SV40 inhibits early stages in the HIV-1 replicative cycle. J Hematother Stem Cell Res. 2002 Oct; 11(5):817-28.
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Fang J, Kubota S, Pomerantz RJ. A trans-dominant negative HIV type 1 Rev with intact domains of NLS/NOS and NES. AIDS Res Hum Retroviruses. 2002 Jul 01; 18(10):705-9.
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McGettigan JP, Sarma S, Orenstein JM, Pomerantz RJ, Schnell MJ. Expression and immunogenicity of human immunodeficiency virus type 1 Gag expressed by a replication-competent rhabdovirus-based vaccine vector. J Virol. 2001 Sep; 75(18):8724-32.
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Chung CW, Rapuano CJ, Laibson PR, Lytle RE, Quirk JT, Cohen EJ. Human immunodeficiency virus p24 antigen testing in cornea donors. Cornea. 2001 Apr; 20(3):277-80.