Macrophages, Alveolar

"Macrophages, Alveolar" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.

Descriptor ID	D016676
MeSH Number(s)	A11.329.372.600 A11.627.482.600 A11.733.397.600 A15.382.680.397.600 A15.382.812.522.600
Concept/Terms	Macrophages, Alveolar Macrophages, Alveolar Pulmonary Macrophages Pulmonary Macrophage Macrophages, Pulmonary Alveolar Macrophages Alveolar Macrophage Macrophage, Alveolar Macrophage, Pulmonary

Below are MeSH descriptors whose meaning is more general than "Macrophages, Alveolar".

Anatomy [A]
Cells [A11]
Connective Tissue Cells [A11.329]
Macrophages [A11.329.372]
Macrophages, Alveolar [A11.329.372.600]
Myeloid Cells [A11.627]
Macrophages [A11.627.482]
Macrophages, Alveolar [A11.627.482.600]
Phagocytes [A11.733]
Macrophages [A11.733.397]
Macrophages, Alveolar [A11.733.397.600]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Phagocytes [A15.382.680]
Macrophages [A15.382.680.397]
Macrophages, Alveolar [A15.382.680.397.600]
Mononuclear Phagocyte System [A15.382.812]
Macrophages [A15.382.812.522]
Macrophages, Alveolar [A15.382.812.522.600]

Below are MeSH descriptors whose meaning is related to "Macrophages, Alveolar".

Below are MeSH descriptors whose meaning is more specific than "Macrophages, Alveolar".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macrophages, Alveolar" by people in this website by year, and whether "Macrophages, Alveolar" was a major or minor topic of these publications.

Bar chart showing 44 publications over 14 distinct years, with a maximum of 5 publications in 2003 and 2005 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1999	2	0	2
2000	1	1	2
2003	5	0	5
2004	0	1	1
2005	4	1	5
2006	1	3	4
2007	2	2	4
2008	3	0	3
2009	3	1	4
2010	2	2	4
2011	4	1	5
2018	1	0	1
2021	0	3	3

Below are the most recent publications written about "Macrophages, Alveolar" by people in Profiles.

Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ. Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies. Cell Stress Chaperones. 2021 09; 26(5):859-868.

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Acheampong KK, Schaff DL, Emert BL, Lake J, Reffsin S, Shea EK, Comar CE, Litzky LA, Khurram NA, Linn RL, Feldman M, Weiss SR, Montone KT, Cherry S, Shaffer SM. Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages. mBio. 2021 02 22; 13(1):e0375121.

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Hall AP, Tepper JS, Boyle MH, Cary MG, Flandre TG, Piaia A, Tarnow I, Macri NP, Freke MC, Nikula KJ, Paul GR, Cauvin A, Gregori M, Haworth R, Naylor S, Price M, Robinson IN, Allen A, Gelzleichter T, Hohlbaum AM, Manetz S, Wolfreys A, Colman K, Fleurance R, Jones D, Mukaratirwa S. BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics. Toxicol Pathol. 2021 02; 49(2):235-260.

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Grunwell JR, Yeligar SM, Stephenson S, Ping XD, Gauthier TW, Fitzpatrick AM, Brown LAS. TGF-?1 Suppresses the Type I IFN Response and Induces Mitochondrial Dysfunction in Alveolar Macrophages. J Immunol. 2018 03 15; 200(6):2115-2128.

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Brown SD, Baxter KM, Stephenson ST, Esper AM, Brown LA, Fitzpatrick AM. Airway TGF-?1 and oxidant stress in children with severe asthma: association with airflow limitation. J Allergy Clin Immunol. 2012 Feb; 129(2):388-96, 396.e1-8.

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Sharma S, Malur A, Marshall I, Huizar I, Barna BP, Pories W, Dohm L, Kavuru MS, Thomassen MJ. Alveolar macrophage activation in obese patients with obstructive sleep apnea. Surgery. 2012 Jan; 151(1):107-12.

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Mehta AJ, Joshi PC, Fan X, Brown LA, Ritzenthaler JD, Roman J, Guidot DM. Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats. Alcohol Clin Exp Res. 2011 Aug; 35(8):1519-28.

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Huizar I, Malur A, Midgette YA, Kukoly C, Chen P, Ke PC, Podila R, Rao AM, Wingard CJ, Dobbs L, Barna BP, Kavuru MS, Thomassen MJ. Novel murine model of chronic granulomatous lung inflammation elicited by carbon nanotubes. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):858-66.

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Fitzpatrick AM, Teague WG, Burwell L, Brown MS, Brown LA. Glutathione oxidation is associated with airway macrophage functional impairment in children with severe asthma. Pediatr Res. 2011 Feb; 69(2):154-9.

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Malur A, Baker AD, McCoy AJ, Wells G, Barna BP, Kavuru MS, Malur AG, Thomassen MJ. Restoration of PPAR? reverses lipid accumulation in alveolar macrophages of GM-CSF knockout mice. Am J Physiol Lung Cell Mol Physiol. 2011 Jan; 300(1):L73-80.

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