"Lipoxygenase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES.
| Descriptor ID |
D016859
|
| MeSH Number(s) |
D27.505.519.389.480
|
| Concept/Terms |
Arachidonate 15-Lipoxygenase Inhibitors- Arachidonate 15-Lipoxygenase Inhibitors
- 15-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 15 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 15-Lipoxygenase
- 15-Lipoxygenase Inhibitors
- 15 Lipoxygenase Inhibitors
- Inhibitors, 15-Lipoxygenase
Arachidonate 5-Lipoxygenase Inhibitors- Arachidonate 5-Lipoxygenase Inhibitors
- 5-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 5 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 5-Lipoxygenase
- 5-Lipoxygenase Inhibitors
- 5 Lipoxygenase Inhibitors
- Inhibitors, 5-Lipoxygenase
Arachidonate 12-Lipoxygenase Inhibitors- Arachidonate 12-Lipoxygenase Inhibitors
- 12-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 12 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 12-Lipoxygenase
- 12-Lipoxygenase Inhibitors
- 12 Lipoxygenase Inhibitors
- Inhibitors, 12-Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Lipoxygenase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Lipoxygenase Inhibitors".
This graph shows the total number of publications written about "Lipoxygenase Inhibitors" by people in this website by year, and whether "Lipoxygenase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Lipoxygenase Inhibitors" by people in Profiles.
-
de Godoy MA, Rattan N, Rattan S. Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter. Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G727-34.
-
Melstrom LG, Bentrem DJ, Salabat MR, Kennedy TJ, Ding XZ, Strouch M, Rao SM, Witt RC, Ternent CA, Talamonti MS, Bell RH, Adrian TA. Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. Clin Cancer Res. 2008 Oct 15; 14(20):6525-30.
-
Hennig R, Grippo P, Ding XZ, Rao SM, Buchler MW, Friess H, Talamonti MS, Bell RH, Adrian TE. 5-Lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions. Cancer Res. 2005 Jul 15; 65(14):6011-6.
-
Waldman SA, Vitow C, Osborne B, Gillen L, Argentieri DC, Wong FA, Smith IL, Chow AT, Misiti J, Bjornsson TD. Pharmacokinetics and pharmacodynamics of tepoxalin after single oral dose administration to healthy volunteers. J Clin Pharmacol. 1996 May; 36(5):462-8.
-
Kane GC, Pollice M, Kim CJ, Cohn J, Dworski RT, Murray JJ, Sheller JR, Fish JE, Peters SP. A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings. J Allergy Clin Immunol. 1996 Feb; 97(2):646-54.
-
Kane GC, Tollino M, Pollice M, Kim CJ, Cohn J, Murray JJ, Dworski R, Sheller J, Fish JE, Peters SP. Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor. Prostaglandins. 1995 Jul; 50(1):1-18.
-
Wright SW, Harris RR, Collins RJ, Corbett RL, Green AM, Wadman EA, Batt DG. Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity. J Med Chem. 1992 Aug 21; 35(17):3148-55.
-
Landolfi R, Mower RL, Steiner M. Modification of platelet function and arachidonic acid metabolism by bioflavonoids. Structure-activity relations. Biochem Pharmacol. 1984 May 01; 33(9):1525-30.