"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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Ottone OK, Kim C, Collins JA, Risbud MV. The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration. Front Immunol. 2022; 13:882407.
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Novais EJ, Tran VA, Johnston SN, Darris KR, Roupas AJ, Sessions GA, Shapiro IM, Diekman BO, Risbud MV. Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nat Commun. 2021 09 03; 12(1):5213.
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Shaghaghi H, Cuevas-Mora K, Para R, Tran C, Roque W, Robertson MJ, Rosas IO, Summer R, Romero F. A model of the aged lung epithelium in idiopathic pulmonary fibrosis. Aging (Albany NY). 2021 07 08; 13(13):16922-16937.
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Xiao P, Huang X, Huang L, Yang J, Li A, Shen K, Wedegaertner PB, Jiang X. G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. Exp Cell Res. 2017 11 15; 360(2):273-280.
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MacFarlane AW, Yamazaki T, Fang M, Sigal LJ, Kurosaki T, Campbell KS. Enhanced NK-cell development and function in BCAP-deficient mice. Blood. 2008 Jul 01; 112(1):131-40.
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Sharma P, Tran T, Stelmack GL, McNeill K, Gosens R, Mutawe MM, Unruh H, Gerthoffer WT, Halayko AJ. Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. Am J Physiol Lung Cell Mol Physiol. 2008 Jan; 294(1):L57-68.
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Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell. 2004 Apr; 5(4):375-87.