"Receptors, Dopamine D2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLYL CYCLASES.
| Descriptor ID |
D017448
|
| MeSH Number(s) |
D12.776.543.750.670.300.400.500 D12.776.543.750.695.150.400.500 D12.776.543.750.720.330.400.500
|
| Concept/Terms |
Receptors, Dopamine D2- Receptors, Dopamine D2
- Dopamine-D2 Receptor
- Dopamine D2 Receptor
- Receptor, Dopamine-D2
- Dopamine D2 Receptors
- D2 Receptors, Dopamine
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Dopamine D2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Dopamine [D12.776.543.750.670.300.400]
- Receptors, Dopamine D2 [D12.776.543.750.670.300.400.500]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Dopamine [D12.776.543.750.695.150.400]
- Receptors, Dopamine D2 [D12.776.543.750.695.150.400.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Dopamine [D12.776.543.750.720.330.400]
- Receptors, Dopamine D2 [D12.776.543.750.720.330.400.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Dopamine D2".
This graph shows the total number of publications written about "Receptors, Dopamine D2" by people in this website by year, and whether "Receptors, Dopamine D2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Dopamine D2" by people in Profiles.
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Chun S, Westmoreland JJ, Bayazitov IT, Eddins D, Pani AK, Smeyne RJ, Yu J, Blundon JA, Zakharenko SS. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science. 2014 Jun 06; 344(6188):1178-82.
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Mathews TA, Brookshire BR, Budygin EA, Hamre K, Goldowitz D, Jones SR. Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse. Alcohol. 2009 Sep; 43(6):421-31.
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Agovic MS, Yablonsky-Alter E, Lidsky TI, Banerjee SP. Mechanisms for metoclopramide-mediated sensitization and haloperidol-induced catalepsy in rats. Eur J Pharmacol. 2008 Jun 10; 587(1-3):181-6.
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Xu H, Kellendonk CB, Simpson EH, Keilp JG, Bruder GE, Polan HJ, Kandel ER, Gilliam TC. DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability. Schizophr Res. 2007 Feb; 90(1-3):104-7.
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Kellendonk C, Simpson EH, Polan HJ, Malleret G, Vronskaya S, Winiger V, Moore H, Kandel ER. Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron. 2006 Feb 16; 49(4):603-15.
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Lloyd SA, Faherty CJ, Smeyne RJ. Adult and in utero exposure to cocaine alters sensitivity to the Parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience. 2006 Feb; 137(3):905-13.
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Guigoni C, Aubert I, Li Q, Gurevich VV, Benovic JL, Ferry S, Mach U, Stark H, Leriche L, H?kansson K, Bioulac BH, Gross CE, Sokoloff P, Fisone G, Gurevich EV, Bloch B, Bezard E. Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors. Parkinsonism Relat Disord. 2005 Jun; 11 Suppl 1:S25-9.
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Loopuijt LD, Hovda DA, Ebrahim A, Villablanca JR, Chugani HT. Differences in D2 dopamine receptor binding in the neostriatum between cats hemidecorticated neonatally or in adulthood. Brain Res Dev Brain Res. 1998 Apr 17; 107(1):113-22.
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Lidsky TI, Yablonsky-Alter E, Zuck LG, Banerjee SP. Antipsychotic drug effects on glutamatergic activity. Brain Res. 1997 Aug 01; 764(1-2):46-52.
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George SR, Cheng R, Nguyen T, Israel Y, O'Dowd BF. Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism. Biochem Biophys Res Commun. 1993 Oct 15; 196(1):107-14.