Receptors, IgG

"Receptors, IgG" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine with IMMUNOGLOBULIN Gs. Three subclasses exist: Fc gamma RI (the CD64 antigen, a low affinity receptor), Fc gamma RII (the CD32 antigen, a high affinity receptor), and Fc gamma RIII (the CD16 antigen, a low affinity receptor).

Descriptor ID	D017452
MeSH Number(s)	D12.776.543.750.705.871.300
Concept/Terms	Receptors, IgG Receptors, IgG IgG Receptors gamma Fc Receptors Fc gamma Receptors gamma Receptors, Fc Receptors, Fc gamma Immunoglobulin G Receptor Receptor, Immunoglobulin G Fc Receptors, gamma Receptors, gamma Fc CD32 Antigens CD32 Antigens CD 32 Antigens Antigens, CD 32 Fc gamma RII gamma RII, Fc Antigens, CD32 Leu-11 Antigens Leu-11 Antigens Antigens, Leu-11 Leu 11 Antigens CD64 Antigens CD64 Antigens CD 64 Antigens Antigens, CD 64 Fc gamma RI gamma RI, Fc Antigens, CD64 Antigens, CD16 Antigens, CD16 Fc gamma RIII gamma RIII, Fc CD 16 Antigens Antigens, CD 16 CD16 Antigens CDw32 Antigens CDw32 Antigens Antigens, CDw32

Below are MeSH descriptors whose meaning is more general than "Receptors, IgG".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Fc [D12.776.543.750.705.871]
Receptors, IgG [D12.776.543.750.705.871.300]

Below are MeSH descriptors whose meaning is related to "Receptors, IgG".

Below are MeSH descriptors whose meaning is more specific than "Receptors, IgG".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, IgG" by people in this website by year, and whether "Receptors, IgG" was a major or minor topic of these publications.

Bar chart showing 186 publications over 30 distinct years, with a maximum of 11 publications in 2015 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	9	0	9
1997	4	2	6
1998	4	4	8
1999	6	0	6
2000	6	2	8
2001	3	0	3
2002	3	2	5
2003	1	6	7
2004	4	2	6
2005	9	1	10
2006	4	5	9
2007	4	6	10
2008	5	1	6
2009	2	2	4
2010	3	3	6
2011	2	2	4
2012	5	1	6
2013	4	2	6
2014	7	2	9
2015	8	3	11
2016	5	2	7
2017	7	4	11
2018	0	5	5
2019	2	3	5
2020	2	2	4
2021	1	4	5
2022	0	1	1
2023	2	4	6
2024	0	2	2
2025	1	0	1

Below are the most recent publications written about "Receptors, IgG" by people in Profiles.

Maskalenko NA, Zahroun S, Tsygankova O, Anikeeva N, Sykulev Y, Campbell KS. The Fc?RIIIA (CD16) L48-H/R Polymorphism Enhances NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity by Promoting Serial Killing. Cancer Immunol Res. 2025 Mar 04; 13(3):417-429.

View in: PubMed
Leung HHL, Ahmadi Z, Lee B, Casey J, Ratnasingam S, McKenzie SE, Perdomo J, Chong BH. Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments. Blood Adv. 2024 11 26; 8(22):5744-5752.

View in: PubMed
Sastre DE, Bournazos S, Du J, Boder EJ, Edgar JE, Azzam T, Sultana N, Huliciak M, Flowers M, Yoza L, Xu T, Chernova TA, Ravetch JV, Sundberg EJ. Potent efficacy of an IgG-specific endoglycosidase against IgG-mediated pathologies. Cell. 2024 Nov 27; 187(24):6994-7007.e12.

View in: PubMed
Osorio JC, Smith P, Knorr DA, Ravetch JV. The antitumor activities of anti-CD47 antibodies require Fc-Fc?R interactions. Cancer Cell. 2023 12 11; 41(12):2051-2065.e6.

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Liu Y, Chen T, Zhu Y, Furey A, Lowary TL, Chan J, Bournazos S, Ravetch JV, Achkar JM. Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan. JCI Insight. 2023 10 23; 8(20).

View in: PubMed
Edgar JE, Trezise S, Anthony RM, Krammer F, Palese P, Ravetch JV, Bournazos S. Antibodies elicited in humans upon chimeric hemagglutinin-based influenza virus vaccination confer Fc?R-dependent protection in vivo. Proc Natl Acad Sci U S A. 2023 10 31; 120(44):e2314905120.

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Knorr K, Rahman J, Erickson C, Wang E, Monetti M, Li Z, Ortiz-Pacheco J, Jones A, Lu SX, Stanley RF, Baez M, Fox N, Castro C, Marino AE, Jiang C, Penson A, Hogg SJ, Mi X, Nakajima H, Kunimoto H, Nishimura K, Inoue D, Greenbaum B, Knorr D, Ravetch J, Abdel-Wahab O. Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia. Nat Cancer. 2023 12; 4(12):1675-1692.

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Yamin R, Kao KS, MacDonald MR, Cantaert T, Rice CM, Ravetch JV, Bournazos S. Human Fc?RIIIa activation on splenic macrophages drives dengue pathogenesis in mice. Nat Microbiol. 2023 08; 8(8):1468-1479.

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Gupta A, Kao KS, Yamin R, Oren DA, Goldgur Y, Du J, Lollar P, Sundberg EJ, Ravetch JV. Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody. Nat Commun. 2023 05 18; 14(1):2853.

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Campana S, De Pasquale C, Sidoti Migliore G, Pezzino G, Cavaliere R, Venanzi Rullo E, Nunnari G, Caramori G, David A, Bonaccorsi I, Pollicino T, Carrega P, Ferlazzo G. Cutting Edge: Hyperinflammatory Monocytes Expressing CD56 Abound in Severe COVID-19 Patients. J Immunol. 2022 08 15; 209(4):655-659.

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