"Ventral Tegmental Area" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A region in the MESENCEPHALON which is dorsomedial to the SUBSTANTIA NIGRA and ventral to the RED NUCLEUS. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the NUCLEUS ACCUMBENS. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of SCHIZOPHRENIA.
Descriptor ID |
D017557
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MeSH Number(s) |
A08.186.211.132.659.413.875.820
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Concept/Terms |
Ventral Tegmental Area- Ventral Tegmental Area
- Tegmental Area, Ventral
- Ventral Tegmental Area of Tsai
- Area Tegmentalis Ventralis
- Area Tegmentalis Ventrali
- Tegmentalis Ventrali, Area
- Tegmentalis Ventralis, Area
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Below are MeSH descriptors whose meaning is more general than "Ventral Tegmental Area".
Below are MeSH descriptors whose meaning is more specific than "Ventral Tegmental Area".
This graph shows the total number of publications written about "Ventral Tegmental Area" by people in this website by year, and whether "Ventral Tegmental Area" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ventral Tegmental Area" by people in Profiles.
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Merlino DJ, Barton JR, Charsar BA, Byrne MD, Rappaport JA, Smeyne RJ, Lepore AC, Snook AE, Waldman SA. Two distinct GUCY2C circuits with PMV (hypothalamic) and SN/VTA (midbrain) origin. Brain Struct Funct. 2019 Nov; 224(8):2983-2999.
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Beier KT, Kim CK, Hoerbelt P, Hung LW, Heifets BD, DeLoach KE, Mosca TJ, Neuner S, Deisseroth K, Luo L, Malenka RC. Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature. 2017 09 21; 549(7672):345-350.
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Quintanilla ME, Rivera-Meza M, Berrios-C?rcamo PA, Bustamante D, Buscaglia M, Morales P, Karahanian E, Herrera-Marschitz M, Israel Y. Salsolinol, free of isosalsolinol, exerts ethanol-like motivational/sensitization effects leading to increases in ethanol intake. Alcohol. 2014 Sep; 48(6):551-9.
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Karahanian E, Rivera-Meza M, Tampier L, Quintanilla ME, Herrera-Marschitz M, Israel Y. Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats. Addict Biol. 2015 Mar; 20(2):336-44.
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Tampier L, Quintanilla ME, Karahanian E, Rivera-Meza M, Herrera-Marschitz M, Israel Y. The alcohol deprivation effect: marked inhibition by anticatalase gene administration into the ventral tegmental area in rats. Alcohol Clin Exp Res. 2013 Aug; 37(8):1278-85.
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Quintanilla ME, Tampier L, Karahanian E, Rivera-Meza M, Herrera-Marschitz M, Israel Y. Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence. Alcohol Clin Exp Res. 2012 Mar; 36(3):517-22.
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Phani S, Gonye G, Iacovitti L. VTA neurons show a potentially protective transcriptional response to MPTP. Brain Res. 2010 Jul 9; 1343:1-13.
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Kaplan GB, Leite-Morris KA, Klufas MA, Fan W. Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity. Eur J Pharmacol. 2009 Jan 14; 602(2-3):268-76.
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Yaroslavsky I, Colletti M, Jiao X, Tejani-Butt S. Strain differences in the distribution of dopamine (DA-2 and DA-3) receptor sites in rat brain. Life Sci. 2006 Jul 17; 79(8):772-6.
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Ward SJ, Martin TJ, Roberts DC. Beta-funaltrexamine affects cocaine self-administration in rats responding on a progressive ratio schedule of reinforcement. Pharmacol Biochem Behav. 2003 May; 75(2):301-7.