"Connexin 43" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.
| Descriptor ID |
D018031
|
| MeSH Number(s) |
D12.776.543.585.250.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Connexin 43".
Below are MeSH descriptors whose meaning is more specific than "Connexin 43".
This graph shows the total number of publications written about "Connexin 43" by people in this website by year, and whether "Connexin 43" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 3 | 1 | 4 |
| 2003 | 2 | 0 | 2 |
| 2005 | 3 | 0 | 3 |
| 2006 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2010 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Connexin 43" by people in Profiles.
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Das S, Shaw AK, Das Sarma S, Koval M, Das Sarma J, Maulik M. Neurotropic Murine ?-Coronavirus Infection Causes Differential Expression of Connexin 47 in Oligodendrocyte Subpopulations Associated with Demyelination. Mol Neurobiol. 2025 Mar; 62(3):3428-3445.
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Karmakar S, Das Sarma J. Human coronavirus OC43 infection remodels connexin 43-mediated gap junction intercellular communication in vitro. J Virol. 2024 07 23; 98(7):e0047824.
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Mulchandani V, Banerjee A, Vadlamannati AV, Kumar S, Das Sarma J. Connexin 43 trafficking and regulation of gap junctional intercellular communication alters ovarian cancer cell migration and tumorigenesis. Biomed Pharmacother. 2023 Mar; 159:114296.
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Bose A, Kasle G, Jana R, Maulik M, Thomas D, Mulchandani V, Mukherjee P, Koval M, Das Sarma J. Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine ?-coronavirus host cell response. J Biol Chem. 2023 02; 299(2):102836.
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Maulik M, Vasan L, Bose A, Dutta Chowdhury S, Sengupta N, Das Sarma J. Amyloid-? regulates gap junction protein connexin 43 trafficking in cultured primary astrocytes. J Biol Chem. 2020 10 30; 295(44):15097-15111.
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Bazzoun D, Adissu HA, Wang L, Urazaev A, Tenvooren I, Fostok SF, Chittiboyina S, Sturgis J, Hodges K, Chandramouly G, Vidi PA, Talhouk RS, Leli?vre SA. Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium. J Cell Sci. 2019 05 16; 132(10).
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Bose A, Basu R, Maulik M, Das Sarma J. Loss of Cx43-Mediated Functional Gap Junction Communication in Meningeal Fibroblasts Following Mouse Hepatitis Virus Infection. Mol Neurobiol. 2018 Aug; 55(8):6558-6571.
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Basu R, Bose A, Thomas D, Das Sarma J. Microtubule-assisted altered trafficking of astrocytic gap junction protein connexin 43 is associated with depletion of connexin 47 during mouse hepatitis virus infection. J Biol Chem. 2017 09 08; 292(36):14747-14763.
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Basu R, Banerjee K, Bose A, Das Sarma J. Mouse Hepatitis Virus Infection Remodels Connexin43-Mediated Gap Junction Intercellular Communication In Vitro and In Vivo. J Virol. 2015 Dec 16; 90(5):2586-99.
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Hamad EA, Li X, Song J, Zhang XQ, Myers V, Funakoshi H, Zhang J, Wang J, Li J, Swope D, Madonick A, Farber J, Radice GL, Cheung JY, Chan TO, Feldman AM. Effects of cardiac-restricted overexpression of the A(2A) adenosine receptor on adriamycin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1738-47.