"Superantigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.
| Descriptor ID |
D018089
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| MeSH Number(s) |
D23.050.820
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Superantigens".
Below are MeSH descriptors whose meaning is more specific than "Superantigens".
This graph shows the total number of publications written about "Superantigens" by people in this website by year, and whether "Superantigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Superantigens" by people in Profiles.
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Schwarzbach HL, Mady LJ, Lee SE. What is the Role of Air Pollution in Chronic Rhinosinusitis? Immunol Allergy Clin North Am. 2020 05; 40(2):215-222.
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Pereira N, Edlind TD, Schlievert PM, Nyirjesy P. Vaginal toxic shock reaction triggering desquamative inflammatory vaginitis. J Low Genit Tract Dis. 2013 Jan; 17(1):88-91.
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Srinivasan A, Bankowski MJ, Seifried SE, Jinno S, Perkins R, Singh S, Ying C, Tice AD, Kim W, Hayden RT. A probe-based method for confirmation of methicillin-resistant Staphylococcus aureus and detection of Panton-Valentine leukocidin and tst virulence genes. Diagn Microbiol Infect Dis. 2011 Aug; 70(4):541-3.