Mice, Inbred mdx

"Mice, Inbred mdx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.

Descriptor ID	D018101
MeSH Number(s)	B01.050.050.199.520.520.420.500 B01.050.150.900.649.313.992.635.505.500.400.420.500 B01.050.150.900.649.313.992.635.505.500.550.265
Concept/Terms	Mice, Inbred mdx Mice, Inbred mdx Inbred mdx Mice Mouse, Inbred mdx Inbred mdx Mouse Mice, mdx mdx Mice Mouse, mdx mdx Mouse

Below are MeSH descriptors whose meaning is more general than "Mice, Inbred mdx".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Laboratory [B01.050.050.199]
Animals, Inbred Strains [B01.050.050.199.520]
Mice, Inbred Strains [B01.050.050.199.520.520]
Mice, Inbred C57BL [B01.050.050.199.520.520.420]
Mice, Inbred mdx [B01.050.050.199.520.520.420.500]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Mice [B01.050.150.900.649.313.992.635.505.500]
Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
Mice, Inbred C57BL [B01.050.150.900.649.313.992.635.505.500.400.420]
Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.400.420.500]
Mice, Mutant Strains [B01.050.150.900.649.313.992.635.505.500.550]
Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.550.265]

Below are MeSH descriptors whose meaning is related to "Mice, Inbred mdx".

Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred mdx".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mice, Inbred mdx" by people in this website by year, and whether "Mice, Inbred mdx" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2000	1	1
2005	1	1
2013	2	2
2014	2	2
2018	1	1

Below are the most recent publications written about "Mice, Inbred mdx" by people in Profiles.

Bauer R, Enns H, Jungmann A, Leuchs B, Volz C, Schinkel S, Koch WJ, Raake PW, Most P, Katus HA, M?ller OJ. Various effects of AAV9-mediated ?ARKct gene therapy on the heart in dystrophin-deficient (mdx) mice and d-sarcoglycan-deficient (Sgcd-/-) mice. Neuromuscul Disord. 2019 03; 29(3):231-241.

View in: PubMed
Sharma P, Basu S, Mitchell RW, Stelmack GL, Anderson JE, Halayko AJ. Role of dystrophin in airway smooth muscle phenotype, contraction and lung function. PLoS One. 2014; 9(7):e102737.

View in: PubMed
Piccioni A, Gaetani E, Palladino M, Gatto I, Smith RC, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R. Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury. Gene Ther. 2014 Apr; 21(4):413-21.

View in: PubMed
He WA, Berardi E, Cardillo VM, Acharyya S, Aulino P, Thomas-Ahner J, Wang J, Bloomston M, Muscarella P, Nau P, Shah N, Butchbach ME, Ladner K, Adamo S, Rudnicki MA, Keller C, Coletti D, Montanaro F, Guttridge DC. NF-?B-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. J Clin Invest. 2013 Nov; 123(11):4821-35.

View in: PubMed
Palladino M, Gatto I, Neri V, Straino S, Smith RC, Silver M, Gaetani E, Marcantoni M, Giarretta I, Stigliano E, Capogrossi M, Hlatky L, Landolfi R, Pola R. Angiogenic impairment of the vascular endothelium: a novel mechanism and potential therapeutic target in muscular dystrophy. Arterioscler Thromb Vasc Biol. 2013 Dec; 33(12):2867-76.

View in: PubMed
Acharyya S, Butchbach ME, Sahenk Z, Wang H, Saji M, Carathers M, Ringel MD, Skipworth RJ, Fearon KC, Hollingsworth MA, Muscarella P, Burghes AH, Rafael-Fortney JA, Guttridge DC. Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell. 2005 Nov; 8(5):421-32.

View in: PubMed
Galbiati F, Volonte D, Chu JB, Li M, Fine SW, Fu M, Bermudez J, Pedemonte M, Weidenheim KM, Pestell RG, Minetti C, Lisanti MP. Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9689-94.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement