Carcinoma, Medullary

"Carcinoma, Medullary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)

Descriptor ID	D018276
MeSH Number(s)	C04.557.465.625.650.240.315 C04.557.470.200.025.370.315 C04.557.470.615.315 C04.557.580.625.650.240.315
Concept/Terms	Carcinoma, Medullary Carcinoma, Medullary Carcinomas, Medullary Medullary Carcinoma Medullary Carcinomas

Below are MeSH descriptors whose meaning is more general than "Carcinoma, Medullary".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neuroendocrine Tumors [C04.557.465.625.650]
Carcinoma, Neuroendocrine [C04.557.465.625.650.240]
Carcinoma, Medullary [C04.557.465.625.650.240.315]
Neoplasms, Glandular and Epithelial [C04.557.470]
Carcinoma [C04.557.470.200]
Adenocarcinoma [C04.557.470.200.025]
Carcinoma, Neuroendocrine [C04.557.470.200.025.370]
Carcinoma, Medullary [C04.557.470.200.025.370.315]
Neoplasms, Ductal, Lobular, and Medullary [C04.557.470.615]
Carcinoma, Medullary [C04.557.470.615.315]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neuroendocrine Tumors [C04.557.580.625.650]
Carcinoma, Neuroendocrine [C04.557.580.625.650.240]
Carcinoma, Medullary [C04.557.580.625.650.240.315]

Below are MeSH descriptors whose meaning is related to "Carcinoma, Medullary".

Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Medullary".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carcinoma, Medullary" by people in this website by year, and whether "Carcinoma, Medullary" was a major or minor topic of these publications.

Bar chart showing 12 publications over 6 distinct years, with a maximum of 3 publications in 2008 and 2009 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2008	2	1	3
2009	2	1	3
2010	2	1	3
2011	1	0	1
2016	1	0	1

Below are the most recent publications written about "Carcinoma, Medullary" by people in Profiles.

Inaguma S, Lasota J, Wang Z, Felisiak-Golabek A, Ikeda H, Miettinen M. Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas. Mod Pathol. 2017 02; 30(2):278-285.

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Gatalica Z, Lilleberg SL, Monzon FA, Koul MS, Bridge JA, Knezetic J, Legendre B, Sharma P, McCue PA. Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes. Hum Pathol. 2011 Dec; 42(12):1979-88.

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O'Kane P, Shelkovoy E, McConnell RJ, Shpak V, Parker L, Brenner A, Zablotska L, Tronko M, Hatch M. Frequency of undetected thyroid nodules in a large I-131-exposed population repeatedly screened by ultrasonography: results from the Ukrainian-American cohort study of thyroid cancer and other thyroid diseases following the Chornobyl accident. Thyroid. 2010 Sep; 20(9):959-64.

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Witt RL. What is the treatment of the lateral neck in clinically localized sporadic medullary thyroid cancer? Laryngoscope. 2010 Jul; 120(7):1286-7.

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Tuttle RM, Ball DW, Byrd D, Daniels GH, Dilawari RA, Doherty GM, Duh QY, Ehya H, Farrar WB, Haddad RI, Kandeel F, Kloos RT, Kopp P, Lamonica DM, Loree TR, Lydiatt WM, McCaffrey J, Olson JA, Parks L, Ridge JA, Shah JP, Sherman SI, Sturgeon C, Waguespack SG, Wang TN, Wirth LJ. Medullary carcinoma. J Natl Compr Canc Netw. 2010 May; 8(5):512-30.

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Winn B, Tavares R, Matoso A, Noble L, Fanion J, Waldman SA, Resnick MB. Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas. Hum Pathol. 2010 Jan; 41(1):123-8.

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Brose MS. Thyroid cancer update: dramatic changes in the treatment of a rare disease. Oncology (Williston Park). 2009 Aug; 23(9):778, 781.

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Adler JT, Cook M, Luo Y, Pitt SC, Ju J, Li W, Shen B, Kunnimalaiyaan M, Chen H. Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta. Mol Cancer Ther. 2009 Apr; 8(4):914-20.

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Greenblatt DY, Cayo MA, Adler JT, Ning L, Haymart MR, Kunnimalaiyaan M, Chen H. Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cells. Ann Surg. 2008 Jun; 247(6):1036-40.

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Bianciotto CG, Demirci HY, Shields CL, Shields JA. Simultaneous eyelid and choroidal metastases 36 years after diagnosis of medullary thyroid carcinoma. Ophthalmic Plast Reconstr Surg. 2008 Jan-Feb; 24(1):62-3.

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