Carcinoma, Signet Ring Cell

"Carcinoma, Signet Ring Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A poorly differentiated adenocarcinoma in which the nucleus is pressed to one side by a cytoplasmic droplet of mucus. It usually arises in the gastrointestinal system.

Descriptor ID	D018279
MeSH Number(s)	C04.557.470.200.025.415 C04.557.470.590.415
Concept/Terms	Carcinoma, Signet Ring Cell Carcinoma, Signet Ring Cell Signet Ring Cell Carcinoma

Below are MeSH descriptors whose meaning is more general than "Carcinoma, Signet Ring Cell".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Glandular and Epithelial [C04.557.470]
Carcinoma [C04.557.470.200]
Adenocarcinoma [C04.557.470.200.025]
Carcinoma, Signet Ring Cell [C04.557.470.200.025.415]
Neoplasms, Cystic, Mucinous, and Serous [C04.557.470.590]
Carcinoma, Signet Ring Cell [C04.557.470.590.415]

Below are MeSH descriptors whose meaning is related to "Carcinoma, Signet Ring Cell".

Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Signet Ring Cell".

Carcinoma, Signet Ring Cell
Krukenberg Tumor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carcinoma, Signet Ring Cell" by people in this website by year, and whether "Carcinoma, Signet Ring Cell" was a major or minor topic of these publications.

Bar chart showing 13 publications over 11 distinct years, with a maximum of 2 publications in 2023 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2009	0	1	1
2011	1	0	1
2012	1	0	1
2013	1	0	1
2014	1	0	1
2016	1	0	1
2018	0	1	1
2022	1	0	1
2023	2	0	2
2024	0	2	2

Below are the most recent publications written about "Carcinoma, Signet Ring Cell" by people in Profiles.

Gallanis AF, Bowden C, Lopez R, Gamble LA, Samaranayake SG, Payne C, Snyder D, Fasaye GA, Joyce S, Broesamle R, Miao N, Miettinen M, Quezado M, Kim SA, Korman L, Heller T, Blakely AM, Hernandez JM, Davis JL. Lessons learned from 150 total gastrectomies for prevention of cancer. J Gastrointest Surg. 2025 Jan; 29(1):101889.

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Nadeem MS, Ali U, Khan A, Wajid I, Riaz O, Azeem MT. Response of various histological types of locally advanced rectal cancer to neoadjuvant multimodality therapy. J Pak Med Assoc. 2024 Jul; 74(7):1240-1244.

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Green BL, Gamble LA, Diggs LP, Nousome D, Patterson JC, Joughin BA, Gasmi B, Lux SC, Samaranayake SG, Miettinen M, Quezado M, Hernandez JM, Yaffe MB, Davis JL. Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis. Mol Cancer Res. 2023 12 01; 21(12):1356-1365.

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Asif B, Sarvestani AL, Gamble LA, Samaranayake SG, Famiglietti AL, Fasaye GA, Quezado M, Miettinen M, Korman L, Koh C, Heller T, Davis JL. Cancer surveillance as an alternative to prophylactic total gastrectomy in hereditary diffuse gastric cancer: a prospective cohort study. Lancet Oncol. 2023 04; 24(4):383-391.

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Puccini A, Poorman K, Catalano F, Seeber A, Goldberg RM, Salem ME, Shields AF, Berger MD, Battaglin F, Tokunaga R, Naseem M, Zhang W, Philip PA, Marshall JL, Korn WM, Lenz HJ. Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets. Oncogene. 2022 06; 41(26):3455-3460.

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Hanada Y, Choi AY, Hwang JH, Draganov PV, Khanna L, Sethi A, Bartel MJ, Goel N, Abe S, De Latour RA, Park K, Melis M, Newman E, Hatzaras I, Reddy SS, Farma JM, Liu X, Schlachterman A, Kresak J, Trapp G, Ansari N, Schrope B, Lee JY, Dhall D, Lo S, Jamil LH, Burch M, Gaddam S, Gong Y, Del Portillo A, Tomizawa Y, Truong CD, Brewer Gutierrez OI, Montgomery E, Johnston FM, Duncan M, Canto M, Ahuja N, Lennon AM, Ngamruengphong S. Low Frequency of Lymph Node Metastases in Patients in the United States With Early-stage Gastric Cancers That Fulfill Japanese Endoscopic Resection Criteria. Clin Gastroenterol Hepatol. 2019 08; 17(9):1763-1769.

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Kopczynski J, Kowalik A, Chlopek M, Wang ZF, G?zdz S, Lasota J, Miettinen M. Oncogenic Activation of the Wnt/?-Catenin Signaling Pathway in Signet Ring Stromal Cell Tumor of the Ovary. Appl Immunohistochem Mol Morphol. 2016 May-Jun; 24(5):e28-33.

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Bamboat ZM, Tang LH, Vinuela E, Kuk D, Gonen M, Shah MA, Brennan MF, Coit DG, Strong VE. Stage-stratified prognosis of signet ring cell histology in patients undergoing curative resection for gastric adenocarcinoma. Ann Surg Oncol. 2014 May; 21(5):1678-85.

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Willis AI, Taghavi S, Jayarajan SN, Davey A. Reply to G. Piessen et al. J Clin Oncol. 2013 Jun 01; 31(16):2060-1.

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Taghavi S, Jayarajan SN, Davey A, Willis AI. Prognostic significance of signet ring gastric cancer. J Clin Oncol. 2012 Oct 01; 30(28):3493-8.

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