Patch-Clamp Techniques

"Patch-Clamp Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

Descriptor ID	D018408
MeSH Number(s)	E05.200.500.905 E05.242.800
Concept/Terms	Patch-Clamp Techniques Patch-Clamp Techniques Patch Clamp Techniques Patch-Clamp Technique Technique, Patch-Clamp Techniques, Patch-Clamp Patch-Clamp Technics Patch Clamp Technics Patch-Clamp Technic Technic, Patch-Clamp Technics, Patch-Clamp Whole-Cell Recording Whole-Cell Recording Recording, Whole-Cell Recordings, Whole-Cell Whole Cell Recording Whole-Cell Recordings Voltage-Clamp Techniques Voltage-Clamp Techniques Technique, Voltage-Clamp Techniques, Voltage-Clamp Voltage Clamp Techniques Voltage-Clamp Technique Voltage-Clamp Technics Technic, Voltage-Clamp Technics, Voltage-Clamp Voltage Clamp Technics Voltage-Clamp Technic

Below are MeSH descriptors whose meaning is more general than "Patch-Clamp Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Cytological Techniques [E05.200.500]
Patch-Clamp Techniques [E05.200.500.905]
Cytological Techniques [E05.242]
Patch-Clamp Techniques [E05.242.800]

Below are MeSH descriptors whose meaning is more specific than "Patch-Clamp Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Patch-Clamp Techniques" by people in this website by year, and whether "Patch-Clamp Techniques" was a major or minor topic of these publications.

Bar chart showing 47 publications over 14 distinct years, with a maximum of 6 publications in 2002 and 2010

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2002	6	6
2003	5	5
2004	2	2
2005	2	2
2006	5	5
2007	4	4
2008	2	2
2009	4	4
2010	6	6
2011	5	5
2012	2	2
2013	2	2
2014	1	1
2017	1	1

Below are the most recent publications written about "Patch-Clamp Techniques" by people in Profiles.

Møller RS, Wuttke TV, Helbig I, Marini C, Johannesen KM, Brilstra EH, Vaher U, Borggraefe I, Talvik I, Talvik T, Kluger G, Francois LL, Lesca G, de Bellescize J, Blichfeldt S, Chatron N, Holert N, Jacobs J, Swinkels M, Betzler C, Syrbe S, Nikanorova M, Myers CT, Larsen LH, Vejzovic S, Pendziwiat M, von Spiczak S, Hopkins S, Dubbs H, Mang Y, Mukhin K, Holthausen H, van Gassen KL, Dahl HA, Tommerup N, Mefford HC, Rubboli G, Guerrini R, Lemke JR, Lerche H, Muhle H, Maljevic S. Mutations in GABRB3: From febrile seizures to epileptic encephalopathies. Neurology. 2017 Jan 31; 88(5):483-492.

View in: PubMed
Tian J, Tep C, Benedick A, Saidi N, Ryu JC, Kim ML, Sadasivan S, Oberdick J, Smeyne R, Zhu MX, Yoon SO. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. J Biol Chem. 2014 Nov 07; 289(45):31458-72.

View in: PubMed
Alzayady KJ, Wagner LE, Chandrasekhar R, Monteagudo A, Godiska R, Tall GG, Joseph SK, Yule DI. Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits. J Biol Chem. 2013 Oct 11; 288(41):29772-84.

View in: PubMed
Hongpaisan J, Xu C, Sen A, Nelson TJ, Alkon DL. PKC activation during training restores mushroom spine synapses and memory in the aged rat. Neurobiol Dis. 2013 Jul; 55:44-62.

View in: PubMed
Deliu E, Brailoiu GC, Arterburn JB, Oprea TI, Benamar K, Dun NJ, Brailoiu E. Mechanisms of G protein-coupled estrogen receptor-mediated spinal nociception. J Pain. 2012 Aug; 13(8):742-54.

View in: PubMed
Edelmayer RM, Le LN, Yan J, Wei X, Nassini R, Materazzi S, Preti D, Appendino G, Geppetti P, Dodick DW, Vanderah TW, Porreca F, Dussor G. Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain. 2012 Sep; 153(9):1949-1958.

View in: PubMed
Jhun BS, O-Uchi J, Wang W, Ha CH, Zhao J, Kim JY, Wong C, Dirksen RT, Lopes CM, Jin ZG. Adrenergic signaling controls RGK-dependent trafficking of cardiac voltage-gated L-type Ca2+ channels through PKD1. Circ Res. 2012 Jan 6; 110(1):59-70.

View in: PubMed
Ryu SY, Beutner G, Kinnally KW, Dirksen RT, Sheu SS. Single channel characterization of the mitochondrial ryanodine receptor in heart mitoplasts. J Biol Chem. 2011 Jun 17; 286(24):21324-9.

View in: PubMed
Nolt MJ, Lin Y, Hruska M, Murphy J, Sheffler-Colins SI, Kayser MS, Passer J, Bennett MV, Zukin RS, Dalva MB. EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner. J Neurosci. 2011 Apr 6; 31(14):5353-64.

View in: PubMed
Ghosh B, Li Y, Thayer SA. Inhibition of the plasma membrane Ca2+ pump by CD44 receptor activation of tyrosine kinases increases the action potential afterhyperpolarization in sensory neurons. J Neurosci. 2011 Feb 16; 31(7):2361-70.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement