CD8-Positive T-Lymphocytes

"CD8-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.

Descriptor ID	D018414
MeSH Number(s)	A11.118.637.555.567.569.220 A15.145.229.637.555.567.569.220 A15.382.490.555.567.569.220
Concept/Terms	CD8-Positive T-Lymphocytes CD8-Positive T-Lymphocytes CD8 Positive T Lymphocytes CD8-Positive T-Lymphocyte T-Lymphocyte, CD8-Positive T-Lymphocytes, CD8-Positive T8 Lymphocytes Lymphocyte, T8 Lymphocytes, T8 T8 Lymphocyte T8 Cells Cell, T8 Cells, T8 T8 Cell CD8-Positive Lymphocytes CD8 Positive Lymphocytes CD8-Positive Lymphocyte Lymphocyte, CD8-Positive Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive CD8-Positive Suppressor T-Lymphocyte CD8-Positive Suppressor T-Lymphocytes Suppressor T Lymphocytes, CD8 Positive Suppressor T-Lymphocyte, CD8-Positive T-Lymphocyte, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor Suppressor T-Cells, CD8-Positive CD8-Positive Suppressor T-Cell CD8-Positive Suppressor T-Cells Suppressor T Cells, CD8 Positive Suppressor T-Cell, CD8-Positive T-Cell, CD8-Positive Suppressor T-Cells, CD8-Positive Suppressor

Below are MeSH descriptors whose meaning is more general than "CD8-Positive T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
CD8-Positive T-Lymphocytes [A11.118.637.555.567.569.220]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD8-Positive T-Lymphocytes [A15.145.229.637.555.567.569.220]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]
CD8-Positive T-Lymphocytes [A15.382.490.555.567.569.220]

Below are MeSH descriptors whose meaning is related to "CD8-Positive T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "CD8-Positive T-Lymphocytes".

CD8-Positive T-Lymphocytes
T-Lymphocytes, Cytotoxic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CD8-Positive T-Lymphocytes" by people in this website by year, and whether "CD8-Positive T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 146 publications over 25 distinct years, with a maximum of 11 publications in 2005 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	0	2	2
2000	1	1	2
2002	3	2	5
2003	2	6	8
2004	3	3	6
2005	2	9	11
2006	6	3	9
2007	3	6	9
2008	3	6	9
2009	5	4	9
2010	2	3	5
2011	8	3	11
2012	3	1	4
2013	6	3	9
2014	3	4	7
2015	1	3	4
2016	2	1	3
2017	2	2	4
2018	1	0	1
2019	2	1	3
2020	3	4	7
2021	4	3	7
2022	0	6	6
2023	1	3	4

Below are the most recent publications written about "CD8-Positive T-Lymphocytes" by people in Profiles.

Sykulev Y. Factors contributing to the potency of CD8+ T cells. Trends Immunol. 2023 09; 44(9):693-700.

View in: PubMed
Kalatskaya I, Giovannoni G, Leist T, Cerra J, Boschert U, Rolfe PA. Revealing the immune cell subtype reconstitution profile in patients from the CLARITY study using deconvolution algorithms after cladribine tablets treatment. Sci Rep. 2023 May 18; 13(1):8067.

View in: PubMed
Kaur S, Awad D, Finney RP, Meyer TJ, Singh SP, Cam MC, Karim BO, Warner AC, Roberts DD. CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells. Int J Mol Sci. 2023 Jan 30; 24(3).

View in: PubMed
Fu Z, Chen S, Zhu Y, Zhang D, Xie P, Jiao Q, Chi J, Xu S, Xue Y, Lu X, Song X, Cristofanilli M, Gradishar WJ, Kalinsky K, Yin Y, Zhang B, Wan Y. Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Sci Adv. 2023 01 06; 9(1):eadd6626.

View in: PubMed
Anikeeva N, Steblyanko M, Kuri-Cervantes L, Buggert M, Betts MR, Sykulev Y. The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection. Nat Commun. 2022 10 28; 13(1):6436.

View in: PubMed
Palatnik-de-Sousa I, Wallace ZS, Cavalcante SC, Ribeiro MPF, Silva JABM, Cavalcante RC, Scheuermann RH, Palatnik-de-Sousa CB. A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to Omicron. Sci Rep. 2022 10 06; 12(1):16731.

View in: PubMed
Nath PR, Pal-Nath D, Kaur S, Gangaplara A, Meyer TJ, Cam MC, Roberts DD. Loss of CD47 alters CD8+ T cell activation in vitro and immunodynamics in mice. Oncoimmunology. 2022; 11(1):2111909.

View in: PubMed
Mare SD, Nishri Y, Shai A, Efrati M, Deutsch L, Den RB, Kelson I, Keisari Y, Domankevich V. Diffusing Alpha-Emitters Radiation Therapy Promotes a Proimmunogenic Tumor Microenvironment and Synergizes With Programmed Cell Death Protein 1 Blockade. Int J Radiat Oncol Biol Phys. 2023 Mar 01; 115(3):707-718.

View in: PubMed
Labrosse R, Boufaied I, Bourdin B, Gona S, Randolph HE, Logan BR, Bourbonnais S, Berthe C, Chan W, Buckley RH, Parrott RE, Cuvelier GDE, Kapoor N, Chandra S, D?vila Salda?a BJ, Eissa H, Goldman FD, Heimall J, O'Reilly R, Chaudhury S, Kolb EA, Shenoy S, Griffith LM, Pulsipher M, Kohn DB, Notarangelo LD, Pai SY, Cowan MJ, Dvorak CC, Haddad ?, Puck JM, Barreiro LB, Decaluwe H. Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation. J Allergy Clin Immunol. 2023 01; 151(1):260-271.

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Principe N, Aston WJ, Hope DE, Tilsed CM, Fisher SA, Boon L, Dick IM, Chin WL, McDonnell AM, Nowak AK, Lake RA, Chee J, Lesterhuis WJ. Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations. Front Immunol. 2022; 13:872295.

View in: PubMed

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