Avinoam Nevler

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentSurgery
Address1025 Walnut St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Brown SZ, McCarthy GA, Carroll JR, Di Niro R, Pelz C, Jain A, Sutton TL, Holly HD, Nevler A, Schultz CW, McCoy MD, Cozzitorto JA, Jiang W, Yeo CJ, Dixon DA, Sears RC, Brody JR. The RNA-Binding Protein HuR Posttranscriptionally Regulates the Protumorigenic Activator YAP1 in Pancreatic Ductal Adenocarcinoma. Mol Cell Biol. 2022 Jun 15; e0001822. PMID: 35703534.
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    2. Saif A, Teke M, Ryan C, Papai E, Nevler A, Hernandez JM, Lavu H. The WASH (Water or Saline at High Volumes) Trial: A Randomized Trial to Assess the Survival Impact of Extensive Peritoneal Lavage Using Distilled Water or Saline at High Volumes After Pancreatic Resection for Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol. 2022 Jun 04. PMID: 35661956.
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    3. Nauheim DO, Hackbart H, Papai E, Moskal D, Yeo CJ, Lavu H, Nevler A. Preoperative sarcopenia is a negative predictor for enhanced postoperative recovery after pancreaticoduodenectomy. Langenbecks Arch Surg. 2022 May 20. PMID: 35593934.
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    4. Nauheim D, Moskal D, Renslo B, Chadwick M, Jiang W, Yeo CJ, Nevler A, Bowne W, Lavu H. KRAS mutation allele frequency threshold alters prognosis in right-sided resected pancreatic cancer. J Surg Oncol. 2022 Mar 25. PMID: 35333412.
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    5. Ponzini F, Kowal L, Ghafoor M, Goldberg A, Chan J, Lamm R, Cannaday SM, Richard SD, Nevler A, Lavu H, Bowne WB, Rosenblum NG. Rare occurrence of pseudomyxoma peritonei (PMP) syndrome arising from a malignant transformed ovarian primary mature cystic teratoma treated by cytoreductive surgery and HIPEC: a case report. World J Surg Oncol. 2022 Mar 11; 20(1):78. PMID: 35272690.
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    6. Russell B, Zager Y, Mullin G, Cohen M, Dan A, Nevler A, Gutman M, Horesh N. Naples Prognostic Score to Predict Postoperative Complications After Colectomy for Diverticulitis. Am Surg. 2022 Jan 03; 31348211069803. PMID: 34979811.
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    7. Papai E, Nevler A, Solomides C, Shergill MS, Yeo TP, Cannaday S, Yeo CJ, Winter JM, Lavu H. Intraoperative Cytologic Sampling for Resected Pancreatic and Periampullary Adenocarcinoma with Implications for Locoregional Recurrence-Free Survival. J Am Coll Surg. 2022 Jan 01; 234(1):48-53. PMID: 35213459.
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    8. Schultz CW, McCarthy GA, Nerwal T, Nevler A, DuHadaway JB, McCoy MD, Jiang W, Brown SZ, Goetz A, Jain A, Calvert VS, Vishwakarma V, Wang D, Preet R, Cassel J, Summer R, Shaghaghi H, Pommier Y, Baechler SA, Pishvaian MJ, Golan T, Yeo CJ, Petricoin EF, Prendergast GC, Salvino J, Singh PK, Dixon DA, Brody JR. The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria. Mol Cancer Ther. 2021 Aug 19. PMID: 34413127.
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    9. Yeo TP, Fogg RW, Shimada A, Marchesani N, Lavu H, Nevler A, Hegarty S, Brody JR, Yeo CJ. The Imperative of Assessing Quality of Life in Patients Presenting to a Pancreaticobiliary Surgery Clinic. Ann Surg. 2021 Jul 02. PMID: 34225301.
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    10. Nerwal T, Goetz A, Nevler A, Barmettler G, Solomides C, Kowalski T, Loren D, Lavu H, Yeo CJ, HooKim K, Winter JM. Accuracy of cytopathology evaluation for resected benign and malignant pancreatic disease. J Surg Oncol. 2021 Sep; 124(3):343-353. PMID: 34120342.
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    11. Haber AO, Jain A, Mani C, Nevler A, Agostini LC, Golan T, Palle K, Yeo CJ, Gmeiner WH, Brody JR. AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition. Mol Cancer Res. 2021 Apr; 19(4):565-572. PMID: 33593942.
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    12. Nevo Y, Shaltiel T, Constantini N, Rosin D, Gutman M, Zmora O, Nevler A. Activity Tracking After Surgery: Does It Correlate With Postoperative Complications? Am Surg. 2021 Jan 30; 3134820988818. PMID: 33522277.
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    13. Agostini LC, Jain A, Shupp A, Nevler A, McCarthy G, Bussard KM, Yeo CJ, Brody JR. Combined targeting of PARG and Wee1 causes decreased cell survival and DNA damage in an S-phase dependent manner. Mol Cancer Res. 2020 Nov 30. PMID: 33257507.
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    14. Zager Y, Khalilieh S, Ganaiem O, Gorgov E, Horesh N, Anteby R, Kopylov U, Jacoby H, Dreznik Y, Dori A, Gutman M, Nevler A. Low psoas muscle area is associated with postoperative complications in Crohn's disease. Int J Colorectal Dis. 2021 Mar; 36(3):543-550. PMID: 33236229.
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    15. Zager Y, Hoffman A, Dreznik Y, Jacoby H, Cordoba M, Horesh N, Nevler A, Gutman M, Berger Y. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from colorectal cancer: The prognostic impact of baseline neutrophil-lymphocyte, platelet-lymphocyte and lymphocyte-monocyte ratios. Surg Oncol. 2020 Dec; 35:321-327. PMID: 32977104.
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    16. Zager Y, Horesh N, Dan A, Aharoni M, Khalilieh S, Cordoba M, Nevler A, Gutman M, Rosin D. Associations of novel inflammatory markers with long-term outcomes and recurrence of diverticulitis. ANZ J Surg. 2020 10; 90(10):2041-2045. PMID: 32856387.
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    17. Nevler A, Brown SZ, Nauheim D, Portocarrero C, Bassig J, Schultz CW, McCarthy G, Lavu H, Yeo TP, Yeo CJ, Brody JR. Effect of Hypercapnia, an Element of Obstructive Respiratory Disorders, on Pancreatic Cancer Chemoresistance and Progression. J Am Coll Surg. 2020 Feb 10. PMID: 32058016.
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    18. Nevler A, Keith SW, Lavu H, Yeo TP, Cannaday S, Yeo CJ, Winter JM. Optimizing cancer cure dialog: an analysis of pancreatic cancer patients' views regarding survival and cure. Support Care Cancer. 2019 Dec 10. PMID: 31823056.
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    19. Jain A, Agostini LC, McCarthy GA, Chand SN, Ramirez A, Nevler A, Cozzitorto J, Schultz CW, Lowder CY, Smith KM, Waddell ID, Raitses-Gurevich M, Stossel C, Gorman YG, Atias D, Yeo CJ, Winter JM, Olive KP, Golan T, Pishvaian MJ, Ogilvie D, James DI, Jordan AM, Brody JR. Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer. Cancer Res. 2019 Jul 04. PMID: 31273064.
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    20. Barda L, Nevler A, Rosin D, Shabtai EL, Gutman M, Shabtai M. [THE EFFECTS OF HORMONAL REPLACEMENT THERAPY (HRT) ON MAMMOGRAPHIC BREAST DENSITY AND ABNORMAL MAMMOGRAMS PROMPTING FURTHER INVESTIGATION]. Harefuah. 2019 Apr; 158(4):239-243. PMID: 31032556.
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    21. McGee HM, Jiang D, Soto-Pantoja DR, Nevler A, Giaccia AJ, Woodward WA. Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop. Clin Cancer Res. 2019 05 15; 25(10):2969-2974. PMID: 30723144.
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    22. Nevler A, Muller AJ, Sutanto-Ward E, DuHadaway JB, Nagatomo K, Londin E, O'Hayer K, Cozzitorto JA, Lavu H, Yeo TP, Curtis MT, Villatoro T, Leiby BE, Mandik-Nayak L, Winter JM, Yeo CJ, Prendergast GC, Brody JR. Host IDO2 gene status influences tumor progression and radiotherapy response in KRAS-driven sporadic pancreatic cancers. Clin Cancer Res. 2018 Sep 28. PMID: 30266763.
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    23. Yeo TP, Lavu H, Nevler A, Brumbaugh J, Vicchairelli D, Winter JM, Brody JR, Yeo CJ. Precious Data: Interim Report from the Jefferson Pancreas Tumor Registry. J Pancreat Cancer. 2018; 4(1):17-24. PMID: 30631853.
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    24. Nevo Y, Goldes Y, Barda L, Nadler R, Gutman M, Nevler A. Risk Factors for Complications of Total/Subtotal Gastrectomy for Gastric Cancer: Prospectively Collected, Based on the Clavien-Dindo Classification System. Isr Med Assoc J. 2018 05; 20(5):277-280. PMID: 29761671.
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    25. Nevler A, Berger Y, Rabinovitz A, Zmora O, Shabtai M, Rosin D, Gutman M. Diagnostic Value of Serum Bilirubin and Liver Enzyme Levels in Acute Appendicitis. Isr Med Assoc J. 2018 Mar; 20(3):176-181. PMID: 29527857.
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    26. Nevler A, Muller AJ, Cozzitorto JA, Goetz A, Winter JM, Yeo TP, Lavu H, Yeo CJ, Prendergast GC, Brody JR. A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2. J Am Coll Surg. 2018 Feb 07. PMID: 29426021.
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    27. Chand SN, Zarei M, Schiewer MJ, Kamath AR, Romeo C, Lal S, Cozzitorto JA, Nevler A, Scolaro L, Londin E, Jiang W, Meisner-Kober N, Pishvaian MJ, Knudsen KE, Yeo CJ, Pascal JM, Winter JM, Brody JR. Post-transcriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors. Cancer Res. 2017 Jul 07. PMID: 28687616.
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    28. Zarei M, Lal S, Parker SJ, Nevler A, Vaziri-Gohar A, Dukleska K, Mambelli-Lisboa NC, Moffat C, Blanco FF, Chand SN, Jimbo M, Cozzitorto JA, Jiang W, Yeo CJ, Londin E, Seifert EL, Metallo CM, Brody JR, Winter JM. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells. Cancer Res. 2017 Jun 26. PMID: 28652247.
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    29. Gazer B, Rosin D, Bar-Zakai B, Willenz U, Doron O, Gutman M, Nevler A. Accuracy and inter-operator variability of small bowel length measurement at laparoscopy. Surg Endosc. 2017 11; 31(11):4697-4704. PMID: 28409379.
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    30. Nevler A, Har-Zahav G, Abraham A, Schiby G, Zmora O, Shabtai M, Gutman M, Rosin D. Laparoscopic Lymph Node Biopsy: Efficacy and Advantages. Isr Med Assoc J. 2017 Apr; 19(4):231-233. PMID: 28480676.
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    31. Lal S, Cheung EC, Zarei M, Preet R, Chand SN, Mambelli-Lisboa NC, Romeo C, Stout MC, Londin E, Goetz A, Lowder CY, Nevler A, Yeo CJ, Campbell PM, Winter JM, Dixon DA, Brody JR. CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype. Mol Cancer Res. 2017 Jun; 15(6):696-707. PMID: 28242812.
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    32. Horesh N, Shwaartz C, Amiel I, Nevler A, Shabtai E, Lebedeyev A, Nadler R, Rosin D, Gutman M, Zmora O. Diverticulitis: does age matter? J Dig Dis. 2016 May; 17(5):313-8. PMID: 27106275.
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    33. Lahat E, Nevler A, Batumsky M, Shapiro R, Zmora O, Gutman M. Diagnosis and management of splenic injury following colonoscopy: algorithm and case series. Tech Coloproctol. 2016 Mar; 20(3):163-9. PMID: 26757901.
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    34. Nevler A, Shabtai E, Rosin D, Hoffman A, Gutman M, Shabtai M. Mammographic Breast Density as a Predictor of Radiological Findings Requiring Further Investigation. Isr Med Assoc J. 2016 Jan; 18(1):32-5. PMID: 26964277.
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    35. Nevler A, Shpitzer SA, Shinhar D, Bilik R. Ileo-Ileal Intussusception caused by an Inverted Meckel's Diverticulum Eliciting a Systemic Vasculitis-Like Response. Isr Med Assoc J. 2015 Oct; 17(10):646-7. PMID: 26665323.
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    36. Nevler A, Har-Zahav G, Rosin D, Gutman M. Safer trocar insertion for closed laparoscopic access: ex vivo assessment of an improved Veress needle. Surg Endosc. 2016 Feb; 30(2):779-782. PMID: 26123325.
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    37. Berger Y, Nevler A, Shwaartz C, Lahat E, Zmora O, Gutman M, Shabtai M. Elevations of serum CA-125 predict severity of acute appendicitis in males. ANZ J Surg. 2016 Apr; 86(4):260-3. PMID: 25962470.
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    38. Nevo Y, Lebedyev A, Nevler A. Ileo-colonic intussusception. ANZ J Surg. 2015 Oct; 85(10):786-7. PMID: 25766499.
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    39. Horesh N, Zbar AP, Nevler A, Haim N, Gutman M, Zmora O. Early experience with laparoscopic lavage in acute complicated diverticulitis. Dig Surg. 2015; 32(2):108-11. PMID: 25765997.
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    40. Ziv Y, Nevler A, Willenz E, Doron O, Zbar A, Shperber A, Sandbank J. A novel porcine model for chemically inducible Crohn's-like reaction. Isr Med Assoc J. 2015 Jan; 17(1):19-23. PMID: 25739171.
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    41. Nevler A, Gutman M, Lebedyev A. Assessment of gel-coated delayed self-gripping mesh. JSLS. 2014 Oct-Dec; 18(4). PMID: 25516704.
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    42. Dreznik Y, Gutman M, Weiss B, Nevler A. Mitochondrial neuro-gastrointestinal encephalomyopathy presenting with recurrent bowel perforations and intra-abdominal abscesses. J Gastrointest Surg. 2014 Nov; 18(11):2054-6. PMID: 25022257.
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    43. Mashiach R, Mezhybovsky V, Nevler A, Gutman M, Ziv A, Khaikin M. Three-dimensional imaging improves surgical skill performance in a laparoscopic test model for both experienced and novice laparoscopic surgeons. Surg Endosc. 2014 Dec; 28(12):3489-93. PMID: 24962860.
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    44. Berger Y, Zbar AP, Lebedyev A, Levi Y, Nevler A, Aderka D, Golan T, Purim O, Brenner B, Natur M, Gutman M. [Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal and appendiceal origin]. Harefuah. 2014 Jun; 153(6):315-9, 368. PMID: 25095601.
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    45. Nevler A. The epidemiology of anal incontinence and symptom severity scoring. Gastroenterol Rep (Oxf). 2014 May; 2(2):79-84. PMID: 24759339.
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    46. Nevler A, Zilberman M. Small bowel obstruction in a woman with a missing percutaneous endoscopic gastrostomy tube. Emerg Med J. 2014 Dec; 31(12):1030. PMID: 24421346.
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    47. Nevler A, Willantz U, Doron O, Sandbank J, Ziv Y. A novel anchoring system for colonic stents: a pilot in vivo study in a porcine model. Tech Coloproctol. 2014 Jun; 18(6):551-6. PMID: 24287642.
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    48. Nevler A, Gluck I, Balint-Lahat N, Rosin D. Recurrent metastatic spread to a percutaneous gastrostomy site in a patient with squamous cell carcinoma of the tongue: a case report and review of the literature. J Oral Maxillofac Surg. 2014 Apr; 72(4):829-32. PMID: 24480766.
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    49. Nevler A, Beer-Gabel M, Lebedyev A, Soffer A, Gutman M, Carter D, Zbar AP. Transperineal ultrasonography in perianal Crohn's disease and recurrent cryptogenic fistula-in-ano. Colorectal Dis. 2013 Aug; 15(8):1011-8. PMID: 23489598.
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    50. Zbar AP, Nevler A. Transtar rectal prolapse excision. Dis Colon Rectum. 2013 Jun; 56(6):e327-8. PMID: 23652760.
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    51. Zbar AP, Nevler A. Response to 'Measurement of anal cushions in continent women'. Colorectal Dis. 2012 Feb; 14(2):253; author reply 253-4. PMID: 22023619.
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