"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
| Descriptor ID |
D019014
|
| MeSH Number(s) |
D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
|
| Concept/Terms |
fas Receptor- fas Receptor
- Receptor, fas
- fas Antigen
- fas Antigens
- APO-1 Antigen
- APO 1 Antigen
- CD95 Antigen
- TNFRSF6 Receptor
- Receptor, TNFRSF6
- Antigens, CD95
- Receptors, fas
- fas Receptors
- Tumor Necrosis Factor Receptor Superfamily, Member 6
- Fas Cell Surface Death Receptor
- CD95 Antigens
|
Below are MeSH descriptors whose meaning is more general than "fas Receptor".
Below are MeSH descriptors whose meaning is more specific than "fas Receptor".
This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "fas Receptor" by people in Profiles.
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Schug ZT, Gonzalvez F, Houtkooper RH, Vaz FM, Gottlieb E. BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane. Cell Death Differ. 2011 Mar; 18(3):538-48.
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Yang J, Jiang Z, Fitzgerald DC, Ma C, Yu S, Li H, Zhao Z, Li Y, Ciric B, Curtis M, Rostami A, Zhang GX. Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. J Clin Invest. 2009 Dec; 119(12):3678-91.
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Gonzalvez F, Schug ZT, Houtkooper RH, MacKenzie ED, Brooks DG, Wanders RJ, Petit PX, Vaz FM, Gottlieb E. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J Cell Biol. 2008 Nov 17; 183(4):681-96.
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Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. Int Immunol. 2008 Oct; 20(10):1279-87.
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Tafani M, Karpinich NO, Serroni A, Russo MA, Farber JL. Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation. J Cell Physiol. 2006 Sep; 208(3):556-65.
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Dhanasekaran A, Al-Saghir R, Lopez B, Zhu D, Gutterman DD, Jacobs ER, Medhora M. Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. Am J Physiol Heart Circ Physiol. 2006 Aug; 291(2):H517-31.
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Kikuchi-Maki A, Yusa S, Catina TL, Campbell KS. KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production. J Immunol. 2003 Oct 01; 171(7):3415-25.
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Anderson DG, Izzo MW, Hall DJ, Vaccaro AR, Hilibrand A, Arnold W, Tuan RS, Albert TJ. Comparative gene expression profiling of normal and degenerative discs: analysis of a rabbit annular laceration model. Spine (Phila Pa 1976). 2002 Jun 15; 27(12):1291-6.
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Zhang B, Prendergast GC, Fenton RG. Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression. Cancer Res. 2002 Jan 15; 62(2):450-8.
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Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL. Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J Biol Chem. 2002 Mar 22; 277(12):10073-82.