fas Receptor

"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.

Descriptor ID	D019014
MeSH Number(s)	D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
Concept/Terms	fas Receptor fas Receptor Receptor, fas fas Antigen fas Antigens APO-1 Antigen APO 1 Antigen CD95 Antigen TNFRSF6 Receptor Receptor, TNFRSF6 Antigens, CD95 Receptors, fas fas Receptors Tumor Necrosis Factor Receptor Superfamily, Member 6 Fas Cell Surface Death Receptor CD95 Antigens

Below are MeSH descriptors whose meaning is more general than "fas Receptor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Death Domain [D12.776.543.750.690]
fas Receptor [D12.776.543.750.690.500]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
fas Receptor [D12.776.543.750.705.852.760.195]

Below are MeSH descriptors whose meaning is related to "fas Receptor".

Below are MeSH descriptors whose meaning is more specific than "fas Receptor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.

Bar chart showing 49 publications over 17 distinct years, with a maximum of 8 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	1	3
1997	5	3	8
1998	1	3	4
1999	2	0	2
2000	3	1	4
2001	3	1	4
2002	1	2	3
2003	2	3	5
2005	1	0	1
2006	2	2	4
2007	0	2	2
2008	2	1	3
2009	0	1	1
2010	0	2	2
2011	0	1	1
2017	1	0	1
2018	1	0	1

Below are the most recent publications written about "fas Receptor" by people in Profiles.

Kou X, Xu X, Chen C, Sanmillan ML, Cai T, Zhou Y, Giraudo C, Le A, Shi S. The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing. Sci Transl Med. 2018 03 14; 10(432).

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Li J, Qian L, Dowling JP, Curcione C, Kurup D, Zhang J. Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis. PLoS One. 2017; 12(3):e0174011.

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Garchow BG, Bartulos Encinas O, Leung YT, Tsao PY, Eisenberg RA, Caricchio R, Obad S, Petri A, Kauppinen S, Kiriakidou M. Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice. EMBO Mol Med. 2011 Oct; 3(10):605-15.

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Schug ZT, Gonzalvez F, Houtkooper RH, Vaz FM, Gottlieb E. BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane. Cell Death Differ. 2011 Mar; 18(3):538-48.

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Patel S, Kramer N, Rosenstein ED. Evolving connective tissue disease influenced by splenectomy: beneath the sword of Dameshek. J Clin Rheumatol. 2010 Sep; 16(6):280-3.

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Yang J, Jiang Z, Fitzgerald DC, Ma C, Yu S, Li H, Zhao Z, Li Y, Ciric B, Curtis M, Rostami A, Zhang GX. Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. J Clin Invest. 2009 Dec; 119(12):3678-91.

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Bedi MS, Alvarez RJ, Kubota T, Sheppard R, Kormos RL, Siegenthaler MP, Feldman AM, McTiernan CF, McNamara DM. Myocardial Fas and cytokine expression in end-stage heart failure: impact of LVAD support. Clin Transl Sci. 2008 Dec; 1(3):245-8.

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Gonzalvez F, Schug ZT, Houtkooper RH, MacKenzie ED, Brooks DG, Wanders RJ, Petit PX, Vaz FM, Gottlieb E. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J Cell Biol. 2008 Nov 17; 183(4):681-96.

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Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. Int Immunol. 2008 Oct; 20(10):1279-87.

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Islam Z, Amuzie CJ, Harkema JR, Pestka JJ. Neurotoxicity and inflammation in the nasal airways of mice exposed to the macrocyclic trichothecene mycotoxin roridin a: kinetics and potentiation by bacterial lipopolysaccharide coexposure. Toxicol Sci. 2007 Aug; 98(2):526-41.

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